Results 41 to 50 of about 10,024,591 (280)

Predicting major adverse limb events in individuals with type 2 diabetes: Insights from the EXSCEL trial [PDF]

, 2021
Aims: Although models exist to predict amputation among people with type 2 diabetes with foot ulceration or infection, we aimed to develop a prediction model for a broader range of major adverse limb events (MALE)—including gangrene, revascularization ...
Buse J.B, Jones W.S, Sattar N, Lokhnygina Y, Pagidipati N.J, Katona B, Weissler E.H, Holman R.R, Clare R.M, Hernandez A.F, Mentz R.J, Patel M.R, Goodman S.G, Iqbal N   +13 more
core   +2 more sources

The role of Klotho and FGF23 in cardiovascular outcomes of diabetic patients with chronic limb threatening ischemia: a prospective study

Scientific Reports, 2023
Cardiovascular complications after lower extremity revascularization (LER) are common in diabetic patients with peripheral arterial disease (PAD) and chronic limb threatening ischemia (CLTI).
Federico Biscetti, Maria Margherita Rando, Andrea Leonardo Cecchini, Maria Anna Nicolazzi, Enrica Rossini, Flavia Angelini, Roberto Iezzi, Luis H. Eraso, Paul J. Dimuzio, Dario Pitocco, Antonio Gasbarrini, Massimo Massetti, Andrea Flex   +12 more
doaj   +1 more source

Association between omentin-1 and major cardiovascular events after lower extremity endovascular revascularization in diabetic patients: a prospective cohort study

Cardiovascular Diabetology, 2020
Background Cardiovascular complications represent the major cause of morbidity and mortality of type 2 diabetes mellitus (T2DM) patients. In particular, peripheral artery disease (PAD) represents a frequent T2DM vascular complication and a risk factor ...
Federico Biscetti, Elisabetta Nardella, Maria Margherita Rando, Andrea Leonardo Cecchini, Flavia Angelini, Alessandro Cina, Roberto Iezzi, Marco Filipponi, Angelo Santoliquido, Dario Pitocco, Raffaele Landolfi, Andrea Flex   +11 more
doaj   +1 more source

Angiogenesis-related proteins as biomarkers for peripheral artery disease

Heliyon, 2023
Background: Angiogenesis plays an important role in peripheral artery disease (PAD) and angiogenesis-related proteins may act as prognostic biomarkers.
Ben Li, Niousha Djahanpour, Abdelrahman Zamzam, Muzammil H. Syed, Shubha Jain, Rawand Abdin, Mohammad Qadura   +6 more
doaj   +1 more source

Real-World Predictors of Major Adverse Cardiovascular Events and Major Adverse Limb Events Among Patients with Chronic Coronary Artery Disease and/or Peripheral Arterial Disease

, 2020
© 2019, Springer Healthcare Ltd., part of Springer Nature. Introduction: Collectively, coronary artery disease (CAD) and peripheral artery disease (PAD) are highly prevalent and are associated with increased risk of major adverse cardiovascular events ...
Zhao, Qi, Leeper, Nicholas J., Ting, Windsor, Berger, Jeffrey, Simpson, Alex, Nordstrom, Beth, Berger, Ariel, Murphy, Brian   +7 more
core   +1 more source

Artificial Intelligence of Arterial Doppler Waveforms to Predict Major Adverse Outcomes Among Patients Evaluated for Peripheral Artery Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Patients with peripheral artery disease are at increased risk for major adverse cardiac events, major adverse limb events, and all‐cause death.
Robert D. McBane, Dennis H. Murphree, David Liedl, Francisco Lopez‐Jimenez, Itzhak Zachi Attia, Adelaide M. Arruda‐Olson, Christopher G. Scott, Naresh Prodduturi, Steve E. Nowakowski, Thom W. Rooke, Ana I. Casanegra, Waldemar E. Wysokinski, Damon E. Houghton, Haraldur Bjarnason, Paul W. Wennberg   +14 more
doaj   +1 more source

Patient safety : Cardio and cerebrovascular risk of major adverse events following exposure to potentially inappropriate medications

, 2022
Chapter 1 introduces what is known about the current challenges of medication management in the elderly, with a special focus on management of potentially inappropriate medications (PIMs) in clinical practice.
Aguiar, João Pedro
core   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Long-Term Adverse Limb Events After Femoral Artery Endovascular Revascularization: The Boston FAROUT Study

Journal of the Society for Cardiovascular Angiography & Interventions
Background: : Patient, lesion, and procedural characteristics may impact the long-term risks of adverse limb outcomes differently after successful endovascular revascularization for lower extremity peripheral artery disease.
Edwin Mandieka, MD, Ramael Ohiomoba, MD, MPH, Piotr Sobieszczyk, MD, Andrew C. Eisenhauer, MD, Thomas Todoran, MD, Scott Kinlay, MBBS, PhD   +5 more
doaj   +1 more source

Vorapaxar for Prevention of Major Adverse Cardiovascular and Limb Events in Peripheral Artery Disease

Journal of Cardiovascular Pharmacology and Therapeutics, 2022
Peripheral artery disease (PAD) is a severe manifestation of atherosclerosis. Patients with PAD are at heightened risk for atherothrombotic complications, including myocardial infarction and stroke (MACE); however, there is also an equal or greater risk ...
Justin T. Morrison MD, Nicholas Govsyeyev MD, MS, CS, Connie N. Hess MD, MHS, Marc P. Bonaca MD, MPH   +3 more
doaj   +1 more source