Results 91 to 100 of about 1,659,809 (298)

Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan   +3 more
wiley   +1 more source

Augmentation strategies for inadequate response in major depressive disorder

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
A substantial number of patient, treated for major depressive disorder (MDD), fail to achieve an adequate response to antidepressant medication. At least 50% of those who begin treatment with antidepressant monotherapy fail to respond and 30% of those ...
Nesrin Dilbaz, Serçin Yalçın Çavuş
doaj  

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

The Efficacy of Moclobemide in Treatment of Major Depression

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
The effectiveness and the tolerence of moclobemde -one of the reversible inhibitors of MAO-A were assessed in an open clinical trial on 19 inpatients with major depression according to DSM.III and with a score of 16 or more on Hamilton Rating Scale of ...
Ayhan EĞRİLMEZ   +3 more
doaj  

The reported use and effectiveness of Hypericum (St John’s wort) on affective symptoms in a depression self-help group [PDF]

open access: yes, 2002
A recent meta-analysis suggested that Hypericum perforatum (St John’s wort) is an effective treatment for mild to moderate depression and may have a superior side-effect profile to some antidepressant drugs.
Baldwin, D.S.   +4 more
core   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

Lycanthropy in Major Depression: A Case Report

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2021
Lycanthropy is a delusive belief that the affected person or others transform into a wolf or other animals. Lycanthropy has been known for over 2000 years.
Vahid Shahriyari   +2 more
doaj  

Severe major depression: a case of neurobrucellosis

open access: yesMedicine Science, 2017
Neurobrucellosis (NB) is a rare complication seen in 2-7% of brucellosis cases. Nervous system involvement can cause many neurological and psychiatric disorders and symptoms such as encephalitis, meningoencephalitis, myelitis/myelopathy, spinal epidural ...
Lara Utku Ince   +3 more
doaj   +1 more source

The Healing Power of Storytelling: An Exploration into the Autoethnographic Process [PDF]

open access: yes, 2017
I came to an epiphany as a writer and a person through autoethnography, a research and writing process that analyzes personal experience in the interest of understanding cultural experience.
Cote, Amanda
core   +1 more source

TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara   +18 more
wiley   +1 more source

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