Results 231 to 240 of about 1,682,375 (348)

Examining potential cellular alterations within the anterior cingulate cortex in major depression and suicide

, 2008
Christa Hercher
openalex   +1 more source

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

Advanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li, Ping Deng, Siyu Hou, Xianbo Xia, Wei Zhao, Xingyu Zhu, Yang Zhang, Chao Wang, Ling Xu, Jinlin Song   +9 more
wiley   +1 more source

Adolescent residential mobility, genetic liability and risk of schizophrenia, bipolar disorder and major depression

, 2020
Diana Paksarian, Betina B. Trabjerg, Kathleen R. Merikangas, Ole Mors, Anders D. Børglum, David M. Hougaard, Merete Nordentoft, Thomas Werge, Carsten Bøcker Pedersen, Preben Bo Mortensen, Esben Agerbo, Henriette Thisted Horsdal   +11 more
openalex   +2 more sources

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

Advanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun, Jia‐Jia Wang, Xiang‐Yu Li, Xin‐Yi Lin, Juan Li, Qiu‐Tong Yu, Zi‐Han Wang, Xue‐Ping Gao, Lei Jin, Wei‐Ke Li, Tian‐Lin Cheng, Juan Deng   +11 more
wiley   +1 more source

Immune and metabolic disturbance as a function of genetic risk and phase of illness in major depression. [PDF]

Brain Behav Immun Health
Howard DM, Gilchrist L, Proitsi P, Paul ER, Heilig M, Östman L, Kämpe R, Hamilton JP.   +7 more
europepmc   +1 more source

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

Advanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang, Meng Teng, Wenxuan He, Lanzhou Li, Yongfeng Zhang, Shimiao Wang, Chunyue Wang, Di Wang   +7 more
wiley   +1 more source

Prevalence and correlates of overweight and obesity in patients with major depression accompanied by abnormal TSH levels. [PDF]

BMC Psychiatry
Cao D, Liu H, Li D, Wang X, Zhang H, Huang Z, Zhang Y, Zhang X.   +7 more
europepmc   +1 more source

Nature‐Inspired Surface Modification Strategy Reverses the Autophagic Flux Impairment of Mitochondrial Transplantation for Attenuating Ischemic Strokes

Advanced Science, EarlyView.
The functionalized starch modifies the mitochondrial surface and encapsulates resveratrol into the cavity of helices, facilitating a novel mitochondrial transplantation platform (MLSR). Upon internalization in recipient cells, MLSR triggers mitophagy and maintains positive autophagic flux through RIP1/RIP3 pathway inhibition.
Nisha Wang, Qiyang Ding, Lei Shi, Ji Xia, Shuyue Zhang, Chenxin Jian, Yixiao Yan, Xiuhua Luo, Jiarui Wang, Ming Cheng, Yiqiong Jia, Hao Tian, Wei Gao   +12 more
wiley   +1 more source

Subgenual anterior cingulate cortex in major depression: a systematic review and meta-analysis of MRI studies with patients and healthy controls. [PDF]

Transl Psychiatry
Demchenko I, Sousa-Ho RL, Baltazar VA, Tailor I, Roy N, Schweizer TA, Kennedy SH, Boutet A, Lozano AM, Dunlop K, Bhat V.   +10 more
europepmc   +1 more source

Lumateperone in the treatment of major depressive disorder and bipolar depression with mixed features: efficacy across symptoms

Suresh Durgam, Susan G Kozauer, Willie Earley, Jason Huo, J.B. Edwards, Lakshmi N. Yatham   +5 more
openalex   +1 more source