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Disentangling Perinatal Depression from General Major Depression: A GWAS Meta-Analysis and Genetic Correlation Approach in European Datasets

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Maina JG   +23 more
europepmc   +1 more source
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Major depressive disorder

Nature Reviews Disease Primers, 2023
Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and physical and cognitive symptoms. People with MDD can have reduced quality of life owing to the disorder itself as well as related medical comorbidities, social factors, and ...
Wolfgang Marx   +6 more
openaire   +6 more sources

Major Depression

Medical Clinics of North America, 2014
Major depression is a common, disabling condition seen frequently in primary care practices. Non-psychiatrist ambulatory providers are increasingly responsible for diagnosing, and primarily managing patients suffering from major depressive disorder (MDD). The goal of this review is to help primary care providers to understand the natural history of MDD,
Susan M, Bentley   +2 more
openaire   +2 more sources

Major Depressive Disorder

New England Journal of Medicine, 2008
Depression is related to the normal emotions of sadness and bereavement, but it does not remit when the external cause of these emotions dissipates, and it is disproportionate to their cause. Classic severe states of depression often have no external precipitating cause.
R H, Belmaker, Galila, Agam
openaire   +2 more sources

Prevention of Major Depression

Annual Review of Clinical Psychology, 2010
Before the 1980s, no randomized controlled trials had been carried out to test whether major depressive episodes could be prevented. In the past 30 years, several trials have reported success in reducing the incidence (the number of new cases) of major depressive episodes. These studies suggest that major depression can be prevented.
Munoz, R.F.   +4 more
openaire   +3 more sources

Major Depression

2021
Utilizing the elements described in the previous chapters, this one applies the IPT approach to patients with major depressive disorder in the setting of the Covid-19 pandemic. Major depression is a common sequela of disaster. Major depression is also the disorder for which IPT was first tested and has been most frequently evaluated, and for which it ...
  +4 more sources

Beyond major depression

Psychological Medicine, 2005
Background. The DSM concept of ‘major depression’ has accrued increased status but demonstrated limited utility since inception.Method. An historical overview of models of depression and the initially perceived advantages presented by the concept of ‘major depression’ are presented before detailing its limitations in application.Results.
openaire   +2 more sources

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