Results 171 to 180 of about 207,642 (302)

Depression Symptom Trajectories in Mothers With the FMR1 Premutation Vary by CGG Repeat Length: A Longitudinal Study of 73 Women Spanning 20–75 Years of Age

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Women with the FMR1 premutation (FXpm) are at heightened genetic vulnerability for depression, with risk compounded by the stressors of parenting a disabled child. Although risk factors persist as FXpm women age, depression in FXpm mothers during midlife and old age is poorly characterized. This study used an accelerated longitudinal design to
Jessica Klusek, Lauren Jenner, Abigail L. Hogan, Laura Friedman, Elizabeth Berry‐Kravis, Flora Tassone, Tatyana Adayev, Amanda J. Fairchild, Jane E. Roberts   +8 more
wiley   +1 more source

Design Considerations for a Phase II Platform Trial in Major Depressive Disorder. [PDF]

Pharm Stat
Freitag MM, Zocholl D, Meyer EL, Gold SM, Roig MB, De Smedt H, Posch M, König F, EU‐PEARL MDD Investigators.   +8 more
europepmc   +1 more source

Obesity among outpatients with Major Depressive Disorder [PDF]

, 2005
George I. Papakostas, Timothy Petersen, Dan V. Iosifescu, Alana M. Burns, Andrew A. Nierenberg, Jonathan E. Alpert, Jerrold F. Rosenbaum, Maurizio Fava   +7 more
openalex   +1 more source

Genomic Analysis of Trichotillomania

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Trichotillomania (TTM) is a psychiatric condition in which people feel an overwhelming urge to pull out their hair, resulting in noticeable hair loss and significant distress. Twin and family studies suggest that TTM is at least partly genetic, but no genome‐wide analyses have been completed.
Matthew W. Halvorsen, Melanie E. Garrett, Michael L. Cuccaro, Allison E. Ashley‐Koch, James J. Crowley   +4 more
wiley   +1 more source

Deciphering transcriptomic signatures in schizophrenia, bipolar disorder, and major depressive disorder. [PDF]

Front Psychiatry
Priyanka, Kumar R, Kumar V, Kumar A, Rana SS.   +4 more
europepmc   +1 more source

Analysis of SNP profiles in patients with major depressive disorder [PDF]

, 2005
Sulev Kõks, Tiit Nikopensius, Kati Koido, Eduard Maron, Signe Altmäe, E. Heinaste, Kristel Vabrit, Veronika Tammekivi, Pille Hallast, Ants Kurg, Jakov Shlik, Veiko Vasar, Andres Metspalu, Eero Vasar   +13 more
openalex   +1 more source

The Role of SLC39A8.p.(Ala391Thr) in Schizophrenia Symptom Severity and Cognitive Ability: Cross‐Sectional Studies of Schizophrenia and the General UK Population

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT The missense SNP NC_000004.12:g.102267552C>T (also known as SLC39A8.p.(Ala391Thr), rs13107325) in SLC39A8 encodes a zinc transporter. This SNP has been linked to schizophrenia and is the likely causal variant for one of the genome‐wide association loci associated with the disorder. Using regression analyses, we tested whether the schizophrenia‐
Sophie E. Smart, Sophie E. Legge, Eilidh Fenner, Antonio F. Pardiñas, Grace Woolway, Amy J. Lynham, Valentina Escott‐Price, Jeremy Hall, Lawrence Wilkinson, Peter Holmans, Michael C. O'Donovan, Michael J. Owen, James T.R. Walters   +12 more
wiley   +1 more source

A preliminary open study of the tolerability and effectiveness of nefazodone in major depressive disorder: Comparing patients who recently discontinued an ssri with those on no recent antidepressant treatment

, 2004
David Mischoulon, Gudrun Opitz, Karen E. Kelly, Maurizio Fava, Jerrold F. Rosenbaum   +4 more
openalex   +1 more source

Cognitive behaviour therapy reduces long term risk of relapse in recurrent major depressive disorder [PDF]

, 2005
Zindel V. Segal, Lucio Bizzini, Guido Bondolfi   +2 more
openalex   +1 more source

Genetics of Response to ECT, TMS, Ketamine and Esketamine

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Treatment‐resistant mood disorders are often managed with intensive interventions that include electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), ketamine, and esketamine, but the role of genetics in clinical response to those interventions is yet to be clearly determined.
Clio E. Franklin, Murat Altinay, Kala Bailey, Mahendra T. Bhati, Brent R. Carr, Susan K. Conroy, Khurshid Khurshid, William M. McDonald, Brian J. Mickey, James W. Murrough, Sean M. Nestor, Thomas Nickl‐Jockschat, Irving M. Reti, Gerard Sanacora, Nicholas T. Trapp, Biju Viswanath, Jesse H. Wright, Peter P. Zandi, James B. Potash   +18 more
wiley   +1 more source