Results 191 to 200 of about 827,746 (374)

The Effects of Allopurinol on Major Depressive Disorder

Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2021
Background and Aim: Major Depressive Disorder (MDD) is the most common mental health condition, with a severe decline in performance, disability, and a 15% risk of suicide.
Farideh Ranjbaran, Hamid Reza Jamilian, Bahman Sadeghi Sade   +2 more
doaj  

Language-Agnostic Analysis of Speech Depression Detection [PDF]

arXiv
The people with Major Depressive Disorder (MDD) exhibit the symptoms of tonal variations in their speech compared to the healthy counterparts. However, these tonal variations not only confine to the state of MDD but also on the language, which has unique tonal patterns. This work analyzes automatic speech-based depression detection across two languages,
arxiv  

P01.105 Alpha-1-acid glycoprotein and suicidality in major depressive disorder [PDF]

, 2000
E. Nieto, Eduard Vieta, Lorelí Álvarez, M. Torra, Cristòbal Gastó   +4 more
openalex   +1 more source

Glycolysis‐Derived Lactate Induces ACSL4 Expression and Lactylation to Activate Ferroptosis during Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Glycolysis‐derived lactate activates nucleus pulposus cell ferroptosis via Histon H3K18la‐mediated ACSL4 transcription and ACSL4 lactylation and aggravate intervertebral disc degeneration. Inhibiting glycolysis via gene silencing or chemical intervention reduces the production of lactate and ameliorates ferroptosis activation and nucleus pulposus ...
Kaiqiang Sun, Yangyang Shi, Chen Yan, Shunmin Wang, Linhui Han, Fudong Li, Ximing Xu, Yuan Wang, Jingchuan Sun, Zijian Kang, Jiangang Shi   +10 more
wiley   +1 more source

Emotional Vietnamese Speech-Based Depression Diagnosis Using Dynamic Attention Mechanism [PDF]

arXiv
Major depressive disorder is a prevalent and serious mental health condition that negatively impacts your emotions, thoughts, actions, and overall perception of the world. It is complicated to determine whether a person is depressed due to the symptoms of depression not apparent.
arxiv  

Response in Relation to Baseline Anxiety Levels in Major Depressive Disorder Treated with Bupropion Sustained Release or Sertraline [PDF]

, 2001
A. John Rush
openalex   +1 more source

S‐ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide‐Induced Depression Via Targeting SIRT2

Advanced Science, EarlyView.
S‐ketamine binds directly to SIRT2, facilitating its interaction with NF‐κB p65. This interaction reduces the acetylation of NF‐κB p65 and inhibits its activation, thereby exerting anti‐inflammatory and antidepressant effects. Created by BioRender.
Cong Lin, Xiaoxuan Zhou, Mingqi Li, Cong Zhang, Haojiang Zhai, Haohong Li, Hongshuang Wang, Xiaohui Wang   +7 more
wiley   +1 more source

PupilSense: Detection of Depressive Episodes Through Pupillary Response in the Wild [PDF]

arXiv
Early detection of depressive episodes is crucial in managing mental health disorders such as Major Depressive Disorder (MDD) and Bipolar Disorder. However, existing methods often necessitate active participation or are confined to clinical settings. Addressing this gap, we introduce PupilSense, a novel, deep learning-driven mobile system designed to ...
arxiv  

Tianeptine and paroxetine in major depressive disorder, with a special focus on the anxious component in depression: an international, 6‐week double‐blind study† [PDF]

, 2001
J.P. Lépine, Carlo Altamura, Marc Ansseau, José Luis Gutiérrez, István Bitter, Malcolm Lader, L Waintraub   +6 more
openalex   +1 more source

Photo‐Biomodulation of the Hippocampus Using Near‐Infrared Laser to Enhance Cognitive Function in Mice

Advanced Science, EarlyView.
Here a transcranial photo‐biomodulation approach is developed using near‐infrared (NIR) laser on hippocampus of mice, revealing significant improvements in learning and memory ability of mice under normal and disease conditions. The improvement results from the high‐density cell‐induced NIR local energy deposition, neuronal activation, and axonogenesis
Wei‐Tong Pan, Han‐Wen Gu, Yan‐Bo Zhou, Sophie Ma, Daqing Ma, Pan‐Miao Liu, Jian‐Jun Yang   +6 more
wiley   +1 more source