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Recidivism in Major Depressive Disorder

Psychotherapy and Psychosomatics, 2010
Background: While recidivism has been well studied in psychotic disorders, little has specifically been done to determine what differences exist between patients admitted multiple times compared with once for major depressive disorder (MDD). Method: The records of patients admitted with MDD to a large military medical center were reviewed during the ...
L A, Labbate, M E, Doyle
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Major depressive disorder: Biomarkers and biosensors

Clinica Chimica Acta, 2023
Depressive disorders belong to highly heterogeneous psychiatric diseases. Loss of in interest in previously enjoyed activities and a depressed mood are the main characteristics of major depressive disorder (MDD). Moreover, due to significant heterogeneity in clinical presentation and lack of applicable biomarkers, diagnosis and treatment remains ...
Dadkhah, Masoomeh   +5 more
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The genetics of major depressive disorder

Current Psychiatry Reports, 2000
There is consistent evidence that major depression is familial and population-based twin studies as well as hospital register-based twin studies find substantial heritability. However, there is also a large proportion of variation in liability left to be explained by nongenetic factors.
G S, Malhi, J, Moore, P, McGuffin
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Major depression and personality disorder

Journal of Affective Disorders, 1991
The authors examined an interview and paper-and-pencil assessment of the DSM-III personality disorders (PDs) in depressed inpatients, and depressed relatives of psychiatric patients and never-ill controls who had a lifetime history of major depression. The rates of PDs according to the Structured Interview for DSM-III Personality Disorders (SIDP) were ...
M, Zimmerman   +4 more
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Ketamine for Major Depressive Disorder

2023
Major Depressive Disorder (MDD) is a leading cause of disability worldwide. Conventional antidepressant treatment is characterised by a significant time to onset of therapeutic action (approximately 2 weeks) and fails to achieve a stable remission of symptoms in one-third of subjects with MDD.
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Major Depressive Disorder in a Preschooler

Journal of the American Academy of Child Psychiatry, 1985
The history and evaluation of a preschool child who meets criteria for major depressive disorder are reported. In addition to describing the multifaceted workup required, the authors acknowledge the developmental issues which makes the diagnosis of depression difficult in this age group.
J H, Kashani, G A, Carlson
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Major depressive disorder

New Directions for Mental Health Services, 1992
AbstractMajor depressive disorder (MDD) is now an accepted disorder in children and adolescents; genetic studies and data that support a dysregulation of one or more neurotransmitter systems suggest that biological factors play an important role in MDD in children and adolescents.
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Subtyping Major Depressive Disorder

Psychotherapy and Psychosomatics, 2010
during their lifetime in epidemiological studies using current criteria [4] . It is unlikely that a syndrome as polymorphic and widely diagnosed as major depressive disorder (MDD) will reflect a single process. Attempts to delineate different forms of depression by statistically analyzing the symptomatology of large samples of patients without taking ...
Pesach, Lichtenberg, R H, Belmaker
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Situational Major Depressive Disorder

Archives of General Psychiatry, 1985
Fifty-seven patients with situational major depression diagnosed by the Research Diagnostic Criteria were compared with 72 subjects with nonsituational major depression on demographic, clinical, and psychosocial variables. The situational patients tended to be younger and had fewer prior episodes of depression and fewer hospitalizations. No differences
R M, Hirschfeld   +4 more
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Epigenetics of Major Depressive Disorder

2020
Epigenetic modifications can alter gene expression through mechanisms that are heritable, but do not involve direct changes in the nucleotide sequence of the genome. Recent findings have suggested that epigenetic modifications are associated with several psychiatric disorders.
Wang K. Z.   +6 more
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