Results 221 to 230 of about 533,533 (336)

The role of cortical midline structure in diagnoses and neuromodulation for major depressive disorder [PDF]

Xinyuan Yan
openalex   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

DU4 THE IMPACT OF DEMOGRAPHICS AND INSURANCE ON QUALITY OF CARE IN PATIENTS WITH MAJOR DEPRESSIVE DISORDER IN A CALIFORNIA MEDICAID PROGRAM

, 2009
MB Nichol, Jingjing Wu, TK Knight, JL Priest, CR Cantrell   +4 more
openalex   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Augmentation of Dopaminergic Agents for Major Depressive Disorder

, 2009
Chi‐Un Pae, Ashwin A. Patkar, Prakash S. Masand   +2 more
openalex   +2 more sources

Symmetry Breaking in Chemical Systems: Engineering Complexity Through Self‐Organization and Marangoni Flows

Advanced Science, EarlyView.
We show that solutal Marangoni flows in thin films climbing the outer surfaces of hydrophilic obstacles break circular Belousov‐Zhabotinsky waves into striking flower‐like patterns. Evaporation‐driven surface‐tension gradients, coupled with gravity, trigger the instability; above a threshold, petal number scales linearly with obstacle diameter ...
Sangram Gore, Binaya R. Paudyal, Duarte Rocha, Mohamed Ali, Nader Masmoudi, Albert J. Bae, Christian Diddens, Detlef Lohse, Oliver Steinbock, Azam Gholami   +9 more
wiley   +1 more source

ω-3 Fatty Acids in Pediatric Major Depressive Disorder: A Randomized Clinical Trial.

JAMA Netw Open
Berger G, Häberling I, Emery S, Albermann M, Baumgartner N, Nalani K, Strumberger M, Wöckel L, Erb S, Bachmann S, Müller-Knapp U, Contin-Waldvogel B, Yamini A, Rhiner B, Drechsler R, Held U, Reeve K, Heinz P, Pauli D, Schmeck K, Hersberger M, Walitza S, Omega-3 pMDD Study Group.   +22 more
europepmc   +1 more source

Sobel neural network for EEG-based major depressive disorder screening. [PDF]

Front Psychiatry
Yang H, Ye Y.
europepmc   +1 more source

OBUSight: Clinically Aligned Generative AI for Ophthalmic Ultrasound Interpretation and Diagnosis

Advanced Science, EarlyView.
OBUSight, a clinically aligned generative AI model that jointly generates reports and predicts diseases through multimodal semantic alignment, was trained and validated on a large multicenter dataset. OBUSight outperformed eight state‐of‐the‐art models, provided clinically reliable reports, enhanced diagnostic efficiency, and achieved performance ...
Xiaocong Liu, An Shao, Bingtao Guan, Ziyao Luo, Weiyi Lai, Xiaoling Huang, Jun Liu, Jie Yan, Huimin Li, Xiangji Pan, Jiawei Wang, Zichang Su, Yih Chung Tham, Jie Yang, Haotian Lin, Juan Ye, Hongxia Xu, Jian Wu   +17 more
wiley   +1 more source

Neurovascular coupling abnormalities in first-episode drug-naïve major depressive disorder patients. [PDF]

BMC Psychiatry
Cai S, Guo Q, Wu X, Fang Y, Zhang Y, Zhou W, Shang D, Chen T, Lv Y, Duan J, Yang H.   +10 more
europepmc   +1 more source