Results 111 to 120 of about 2,150,571 (294)

The Dimensions of American Constitutional Equality [PDF]

open access: yes, 1992
Liberty and equality are the hallmark characteristics of any legal order. Constitutional equality in the US is discussed.
Wilkinson, J. Harvie, III
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Proposal Power and Majority Rule in Multilateral Bargaining with Costly Recognition [PDF]

open access: yes
This paper studies a sequential bargaining model in which, as in the rent-seeking literature, agents expend resources to be the proposer, and agreement requires affirmative votes of either all agents or a subset of them.
Yildirim, Huseyin
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Bentham Was Right. Was He?

open access: yesAge of Human Rights Journal, 2015
The importance that the majority principle occupies in Bentham’s theory reveals how it was in tune with what others thought about this principle. I will discuss only the role that this principle holds in Kelsen. For him, the majority principle is central
José J. Jiménez Sánchez
doaj  

Ambiguities, Built-In Biases, and Flaws in Big Data Insight Extraction

open access: yesInformation
I address the challenge of extracting reliable insights from large datasets using a simplified model that illustrates how hierarchical classification can distort outcomes. The model consists of discrete pixels labeled red, blue, or white.
Serge Galam
doaj   +1 more source

Majority Rule in a Stochastic Model of Bargaining [PDF]

open access: yes
In this paper we consider multilateral stochastic bargaining models with general agreement rules. For n-player games where in each period a player is randomly selected to allocate a stochastic level of surplus and qNONCOOPERATIVE BARGAINING; VOTING RULES;
Eraslan, H., Merlo, A.
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Manipulations in Democracy?

open access: yesBehavioral Sciences
Democracy is upheld through the principle of majority rule. To validate the application of democracy, it is imperative to assess the sincerity of voter decisions.
Ruth Ben-Yashar
doaj   +1 more source

A note on choosing the alternative with the best median evaluation [PDF]

open access: yes
The voting rule proposed by Basset and Persky (Public Choice 99: 299-310) picks the alternative with best median evaluation. The present note shows that this MaxMed principle is equivalent to ask the social planner to apply the MaxMin principle allowing ...
Jean-François Laslier
core  

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