Results 81 to 90 of about 4,376,499 (301)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Kültürel-Tarihsel Kuram’a Göre “ – Mış Gibi Oyunlar”: Okul Öncesi Öğretmenlerinin Eğilimlerinin İncelenmesi

open access: yesSakarya University Journal of Education, 2018
Eğitim ortamında hatırlatıcıları, ipuçlarını vedışsal desteği sunan birçok bağlamsal faktör bulunmaktadır. Hiç kuşkusuz bubağlamsal faktörlerin başında öğretmenler, çocuklar ve fiziksel çevregelmektedir.
Sadiye Keleş   +2 more
doaj   +1 more source

Building a Movement: The Lessons of Fines and Fees [PDF]

open access: yes, 2019
I doubt we will ever experience something we (or others) would call an Access to Justice Movement in the United States. The goal is too amorphous, lacks immediacy, and doesn’t resonate: If people don’t perceive that many of their problems have a legal ...
Foster, Lisa
core   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Bibliometric evaluation of research performance: where do we stand?

open access: yes, 2017
This work provides a critical examination of the most popular bibliometric indicators and methodologies to assess the research performance of individuals and institutions.
Abramo, Giovanni
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Video Styles and Learning [PDF]

open access: yes, 2018
With the current prevalence of online and distance learning, videos are becoming a larger part of our education system. It is important that we be able to fully utilize the potential of videos as education tools.
Beckley, David, Marshall, Jeremy
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Metatheatre in Brian Friel’s The Loves of Cass McGuire: The Semiotics of Make-Believe

open access: yesELOPE
The purpose of the present paper is to explore the metatheatrical techniques in The Loves of Cass McGuire by Brian Friel. Those include the play-within-a-play, expressionism, as well as the self-reflexive techniques of Brecht’s and Pirandello’s ...
Mahasen Badra
doaj   +1 more source

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