Results 71 to 80 of about 21,379,830 (325)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Choice history biases in dyadic decision making
How do we interact with our environment and make decisions about the world around us? Empirical research using psychophysical tasks has demonstrated that our perceptual decisions are influenced by past choices, a phenomenon known as the “choice history ...
Ann Huang +4 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Oral History with Brian Randell
Transcript, 31 pp.Brian Randell tells about his upbringing and his work at English Electric, IBM, and Newcastle University. The primary topic of the interview is his work in the history of computing.
Randell, Brian
core
2024 State Flood Plan: History in the Making
In August 2024, the Texas Water Development Board adopted the 2024 State Flood Plan, providing the first-ever comprehensive statewide assessment of flood risk and solutions to reduce the risk and impact to life and property due to flooding.
Texas Water Development Board
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Ohio History Center Groundbreaking photographs
Governor James Rhodes used an Ohio-shaped shovel to turn the first earth for the new Ohio History Center, shown here on on August 22, 1966. The Ohio Historical Society (now the Ohio History Connection) moved to the new building, located near the Ohio ...
Ohio History Connection
core
TEACHING HISTORY WITH NEWSPAPERS: MAKING INVESTIGATIVE PERCEPTIONS.
The relationship between issues for teaching History and historical sourceshas handed me to think about newspapers as a great ally in my work as a teacher.
Raquel França dos Santos Ferreira
doaj
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source

