Results 51 to 60 of about 3,716,942 (293)

El sufrimiento y el perdón. Aportes levinasianos

open access: yesHumanidades, 2017
Este artículo tiene como objeto situar y problematizar lo que es para mí uno de los temas más importantes de nuestro tiempo: el sufrimiento, entendido como mal, y el perdón, como recurrencia al Bien.
Analía Giménez Giubbani
doaj   +1 more source

Testing local-realism and macro-realism under generalized dichotomic measurements

open access: yes, 2018
Generalised quantum measurements with two outcomes are fully characterised by two real parameters, dubbed as sharpness parameter and biasedness parameter and they can be linked with different aspects of the experimental setup.
Das, Debarshi   +2 more
core   +1 more source

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

open access: yesAdvanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin   +12 more
wiley   +1 more source

¿Son convincentes los argumentos de Epicuro y Lucrecio para rechazar el temor a la muerte?

open access: yesAreté, 2022
Este artículo se ocupa de reconstruir y evaluar los principales argumentos epicúreos contra la idea de que la muerte es un mal para quien muere. Para combatir la vida angustiada por el temor a la muerte, Epicuro y Lucrecio despliegan una serie de ...
Sergi Rosell
doaj  

Sovereignty by Subtraction: The Multilateral Agreement on Investment [PDF]

open access: yes, 1998
The proposed Multilateral Agreement on Investment (MAl) represents a major step in the evolution of sovereignty, which includes the power of a nation-state to govern without external controls.
Stumberg, Robert
core   +2 more sources

A Radioresistant‐Tumor‐Targeted Nanoparticle for X‐Ray‐Controlled Nitric Oxide Release to Potentiate Radiotherapy

open access: yesAdvanced Science, EarlyView.
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang   +10 more
wiley   +1 more source

Nicotinamide and Pyridoxine Supplementation Enhances Muscle Stem Cell Activity and Muscle Regeneration in Humans: A Randomized Placebo‐Controlled Clinical Trial of High Force Eccentric Contraction Recovery in Healthy Young Men

open access: yesAdvanced Science, EarlyView.
In a randomized clinical trial, we test the potential of combined nicotinamide (NAM) and pyridoxine (PN) to improve muscle recovery through muscle stem cell (MuSC) activity. Daily oral NAM and PN supplementation after high intensity muscle contractions enhances MuSC activation and differentiation, and accelerates muscle regeneration, providing new ...
Grith Højfeldt   +14 more
wiley   +1 more source

Sula, a Dark Lady

open access: yesOdisea, 2017
: Through Sula (the main character of Toni Morrison’s eponymous novel), Morrison reinterprets the concept of the Dark Lady of the traditional Gothic romance. She is a demonic female, who defi es the Law of the Father in her search for identity.
Manuela López Ramírez
doaj   +1 more source

Mal absoluto, mal radical, banalidad del mal. La comprensión del mal en Hannah Arendt

open access: yesBajo Palabra, 2019
The aim of this article is to provide a panoramic exposition of Hannah Arendt’s thought about the issue of evil. In order to achieve this task, I will pose briefly Kant’s approach of ‘radical evil’, which had an enormous relevance for Arendt. Then, I will point out the stance held by her in The Origins of Totalitarianism and later to explain the way ...
openaire   +3 more sources

Inhibiting cGAS‐STING to Preserve Mitochondrial–Nuclear Communication and Stemness in Young Tendon Stem Cells: A Hydrogel Strategy against Age‐Related Tendinopathy

open access: yesAdvanced Science, EarlyView.
A dual‐targeting strategy to rejuvenate aged tendons. A reactive oxygen species (ROS)‐responsive hydrogel co‐delivers a selenium nanozyme (scavenges ROS) and a STING inhibitor to tendon stem cells. This combined action restores mitochondria–nucleus communication, alleviates cellular senescence, and rejuvenates tendon regeneration, offering a novel ...
Zhuo Zhang   +11 more
wiley   +1 more source

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