Results 111 to 120 of about 242,726 (257)

The epidemiology of malaria in adults in a rural area of southern Mozambique. [PDF]

, 2007
BACKGROUND: Epidemiological studies of malaria in adults who live in malaria endemic areas are scarce. More attention to the natural history of malaria affecting adults is needed to understand the dynamics of malaria infection and its interaction with ...
Fogg Carole, Saute, F., Saúte Francisco, Martinho Dgedge, Alonso Pedro L, Aponte, J., Francisco Saúte, Clara Menendez, Menendez, C., Mayor, A., Alfredo Mayor, John J Aponte, Mayor Alfredo, Alonso, P., Pedro L Alonso, Dgedge Martinho, Greenwood, Brian, Dgedge, Martinho, Carole Fogg, Brian Greenwood, Fogg, Carole, Aponte John J, Dgedge, M., Saúte, Francisco, Greenwood Brian, Aponte, John J, Menendez Clara, Menendez, Clara, Alonso, Pedro L, Mayor, Alfredo, Greenwood, B.   +30 more
core   +1 more source

CLINICAL PRESENTATION AND OUTCOME OF 100 CASES OF FALCIPARUM MALARIA

Khyber Medical University Journal, 2012
Objective: To evaluate the clinical presentation and outcome of Falciparum malaria in 100 hospitalized patients. Methodology: This hospital based descriptive study was conducted at Department of Medicine, Khyber Teaching Hospital, Peshawar from January ...
Iqbal Haider, Muhammad Saleem, imran khan, Fazli subhan, iftikhar muhammad, shahzad ahmad, Aliena badshah   +6 more
doaj  

Peptide‐Enabled Nanoplatforms for Malaria and Leishmaniasis: From Intracellular Targeting to Translational Diagnostic Perspectives

ChemMedChem, Volume 21, Issue 18, 28 September 2026.
Peptide‐enabled nanoplatforms offer multifunctional strategies for the treatment and diagnosis of malaria and leishmaniasis. Liposomal, polymeric, and metallic nanocarriers, together with cell‐penetrating peptides and parasite‐derived mimotopes, can improve targeted drug delivery, stability, bioavailability, and intracellular localization.
Christian S. Carnero Canales, Ana Clara Lunardi Yagi, Túlio Custódio Reis, Jessica Ingrid Cazorla, Jade Rojas Villar, Marcia A. Graminha, Roxana Yesenia Pastrana Alta, Fernando Rogério Pavan   +7 more
wiley   +1 more source

Malaria in pregnancy.

, 2005
Malaria in pregnancy is one of the major causes of maternal morbidity worldwide, and leads to poor birth outcomes. There is a complex interaction between pregnancy and parasite-all favour the parasite and disadvantage the pregnant woman.
Jesus R. Alvarez, Mutabingwa, Theonest K, Laurence Shaw, Whitty, Christopher JM, Joseph J. Apuzzio, Edmonds, Sally, Abdulla Al-Khan   +6 more
core   +1 more source

N8‐Modified Quino[4,3,2‐Kl]acridines as Promising Antimalarial G‐Quadruplex Ligands

ChemBioChem, Volume 27, Issue 17, 14 September 2026.
A series of extended aromatic compounds with tunable substituents was synthesized using a multistep methodology which allows various substitutions of the 8H‐quino[4,3,2‐kl]acridine scaffold. This chemical series appeared as a promising way to new antimalarial drug candidates with high activity (IC50 < 100 nM), exhibiting a novel mechanism of action ...
Steve Saulnier, Marco Antônio G. B. Gomes, Mariam Salim, Maxime Guichonnet, Michel Nguyen, Laure Vendier, Flore Nardella, Jean‐Michel Augereau, Dennis Gomez, Anne Robert, Françoise Benoit‐Vical   +10 more
wiley   +1 more source

Neutralization of malaria glycosylphosphatidylinositol in vitro by serum IgG from malaria-exposed individuals.

, 2010
Parasite-derived glycosylphosphatidylinositol (GPI) is believed to be a major inducer of the pathways leading to pathology and morbidity during Plasmodium falciparum infection and has been termed a malaria "toxin." The generation of neutralizing anti-GPI
Couper, Kevin N, Sanjeev Kumar, Riley, Eleanor M, Runglall, Manohursingh, Corran, Patrick H., J. Brian de Souza, De Souza, J. Brian, Kevin N. Couper, Lucy C. Okell, Kumar, Sanjeev, de Souza, J Brian, Gowda, D. Channe, Eleanor M. Riley, Riley, Eleanor M., Okell, Lucy C, Corran, Patrick H, Patrick H. Corran, Okell, Lucy C., Couper, Kevin N., Gowda, D Channe, Manohursingh Runglall, D. Channe Gowda   +21 more
core   +1 more source

Association between thrombocytopaenia and Plasmodium falciparum infection in Ghana

Scientific Reports
Malaria caused by Plasmodium falciparum is a major global health challenge, often causing significant haematological disturbances. These changes, such as anaemia and thrombocytopenia, reflect the host’s response to infection and can influence disease ...
Richard Vikpebah Duneeh, Shadrack Tetteh Amoada, Elizabeth Yankey, Joshua Appiah Asante, Emmanuel Alote Allotey, Elliot Elikplim Akorsu, Mercy Adzo Klugah, Kenneth Ablordey   +7 more
doaj   +1 more source

FBN30 in wild Anopheles gambiae functions as a pathogen recognition molecule against clinically circulating Plasmodium falciparum in malaria endemic areas in Kenya

Scientific Reports, 2017
Malaria is a worldwide health problem that affects two-thirds of the world population. Plasmodium invasion of anopheline mosquitoes is an obligatory step for malaria transmission.
Guodong Niu, Genwei Zhang, Caio Franca, Yingjun Cui, Stephen Munga, Yaw Afrane, Jun Li   +6 more
doaj   +1 more source

Synthesis and Evaluation of Peptoid‐Based Compound Libraries as Inhibitors of Parasite Metallo‐Aminopeptidases

ChemMedChem, Volume 21, Issue 17, 14 September 2026.
Evaluation of two libraries of peptoid‐based compounds for inhibitory activity against PfA‐M1 from Plasmodium falciparum, TcLAP from Trypanosoma cruzi, and LmLAP from Leishmania major reveals the crucial role of hydrophobic interactions in the inhibition process of these parasite metallo‐aminopeptidases.
Mirta Elisa Aguado, Gerardo M. Ojeda‐Carralero, Mario Antonio Rodríguez, Isabella Rúa, Heisy Guerra, Edoardo Bailo Hernández, Guglielmo Coppola, Susana Alberti, Ariatne Rodríguez, Maikel Izquierdo, Christian Betzel, Filippo Pettazzi, Julieta Coro‐Bermello, Erik V. Van der Eycken, Bernhard Westermann, Jorge González‐Bacerio, Daniel G. Rivera   +16 more
wiley   +1 more source

Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes [PDF]

, 2008
Difficulties with inducing sterile and long lasting protective immunity against malaria with subunit vaccines has renewed interest in vaccinations with attenuated <i>Plasmodium</i> parasites.
Melissa R van Dijk, Ben C L van Schaijk, Geert-Jan van Gemert, Yalaoui Samir, Schaijk, B.C.L. van, Waters, A.P., van Gemert, G. J., Franetich Jean-Francois, Samir Yalaoui, Shahid M Khan, van de Vegte-Bolmera, M., Silvie, O., Hoffman, S. L., Franetich, J.F., van Gemert Geert-Jan, Janse, C.J., Vegte-Bolmer, M.G. van de, Yalaouic, S., Khan, S. M., Chris J Janse, Stephen L Hoffman, Sauerwein Robert W., Silvie Olivier, Sauerwein, R. W., Robert W Sauerwein, Andrew P Waters, Hoffman, S.L., van Dijk, M. R., Waters Andrew P., Sauerwein, R.W., Jean-Francois Franetich, Gemert, G.J.A. van, van de Vegte-Bolmer Marga, Khan, S.M., Olivier Silvie, Mazier, D., Gegoc, A., Gego, A., Khan Shahid M., Franetich, J. F., Dijk, M.R. van, Dominique Mazier, Audrey Gego, Yalaoui, S., Waters, A. P., Janse, C. J., van Schaijk Ben C. L., van Dijk Melissa R., van Schaijk, B. C. L., Janse Chris J., Gego Audrey, Mazier Dominique, Marga van de Vegte-Bolmer, Hoffman Stephen L.   +53 more
core   +3 more sources