Results 81 to 90 of about 270,836 (221)

Molecular epidemiology of Plasmodium vivax and Plasmodium falciparum malaria among Duffy-positive and Duffy-negative populations in Ethiopia

Malaria Journal, 2015
Malaria is the most prevalent communicable disease in Ethiopia, with 75% of the country’s landmass classified as endemic for malaria. Accurate information on the distribution and clinical prevalence of Plasmodium vivax and Plasmodium falciparum malaria ...
Eugenia Lo, Delenasaw Yewhalaw, Daibin Zhong, E. Zemene, T. Degefa, K. Tushune, Margaret Ha, Ming-Chieh Lee, A. James, G. Yan   +9 more
semanticscholar   +1 more source

The cerebellum in epilepsy

Epilepsia, EarlyView.
Abstract The cerebellum, a subcortical structure, is traditionally linked to sensorimotor integration and coordination, although its role in cognition and affective behavior, as well as epilepsy, is increasingly recognized. Cerebellar dysfunction in patients with epilepsy can result from genetic disorders, antiseizure medications, seizures, and seizure‐
Christopher Elder, Rebecca Kerestes, Puneet Opal, Maria Marchese, Orrin Devinsky   +4 more
wiley   +1 more source

Development of cultured Plasmodium falciparum blood-stage malaria cell banks for early phase in vivo clinical trial assessment of anti-malaria drugs and vaccines

Malaria Journal, 2015
BackgroundThe ability to undertake controlled human malaria infection (CHMI) studies for preliminary evaluation of malaria vaccine candidates and anti-malaria drug efficacy has been limited by the need for access to sporozoite infected mosquitoes ...
D. Stanisic, X. Liu, S. De, M. Batzloff, Tanya Forbes, Christopher B Davis, S. Sekuloski, M. Chavchich, Wendy Y. Chung, K. Trenholme, J. McCarthy, Tao Li, B. Kim, Lee Sim, S. Hoffman, M. Good   +15 more
semanticscholar   +1 more source

From fat storage to immune hubs: the emerging role of adipocytes in coordinating the immune response to infection

The FEBS Journal, Volume 292, Issue 8, Page 1868-1883, April 2025.
Traditionally, adipocytes have been viewed as energy storage units, which upregulate inflammatory factors in response to obesity. However, emerging evidence demonstrates that adipocytes are highly responsive to systemic infection, and upregulate cytokines and antimicrobial compounds in response.
Matthew C. Sinton, Shingo Kajimura
wiley   +1 more source

Probing the Clinical, Laboratory, and Sociodemographic Factors Associated with Malaria: A Case-Control Study

Journal of Pharmacy and Bioallied Sciences
Background: The National Malaria Elimination Program (NMEP) has helped reduce the mortality from malaria in India, and there are alarmingly high mortality rates from anemia in certain geographical regions.
Ritesh Upadhyay, Annasaheb J. Dhumale, Chanchlesh Dehariya, Renu Waghmare, Amit Rangari   +4 more
doaj   +1 more source

Epidemiologia de la malaria falciparum complicada: estudio de casos y controles en Tumaco y Turbo, Colombia, 2003

, 2006
OBJETIVOS: Identificar aspectos del hospedero, del parasito y del ambiente asociados con ocurrencia de malaria por Plasmodium falciparum complicada. METODOS: Estudio de casos y controles en pacientes de Tumaco y Turbo (Colombia) aplicando los criterios ...
Alberto Tobón C., Carolina Giraldo S., Juan Gabriel Pineros J., Margarita Arboleda N., Silvia Blair T., J. Carmona-Fonseca   +5 more
semanticscholar   +1 more source

Acute kidney injury in imported Plasmodium falciparum malaria

Malaria Journal, 2015
Acute kidney injury (AKI) is a known complication of malaria, and is reported to occur in up to 40 % of adult patients with a severe Plasmodium falciparum infection in endemic regions.
Liese C. Koopmans, Marlies E. van Wolfswinkel, D. Hesselink, E. Hoorn, R. Koelewijn, J. V. van Hellemond, P. V. van Genderen   +6 more
semanticscholar   +1 more source

Structure–activity analysis of imino‐pyrimidinone‐fused pyrrolidines aids the development of dual plasmepsin V and plasmepsin X inhibitors

The FEBS Journal, EarlyView.
Compounds were identified that inhibit the aspartic protease plasmepsin V from Plasmodium vivax. Further development of these compounds identified compounds, such as S‐WM48, that could inhibit both plasmepsin V and plasmepsin X but plasmepsin IX was not significantly inhibited.
Anthony N. Hodder, Brad E. Sleebs, Greg Adams, Sina Rezazadeh, Anna Ngo, Kate Jarman, Stephen Scally, Peter Czabotar, Hongwu Wang, John A. McCauley, David B. Olsen, Alan F. Cowman   +11 more
wiley   +1 more source

The Diagnostic Performance of a Sysmex XN‐31 Automated Malaria Analyzer vs. Expert Microscopy

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Malaria is a common and life‐threatening infection. Malaria diagnosis needs to be fast and reliable. Although malaria microscopy is currently the gold standard, it is laborious, requires extensive training, and relies heavily on the proficiency of microscopists.
S. Onsongo, K. Otieno, L. Mathenge, E. Makotsi, G. Kariuki, V. Ngetich, G. Muriithi, A. T. Harrison, T. Odawo, S. Kariuki   +9 more
wiley   +1 more source

Imaging malaria parasites across scales and time

Journal of Microscopy, EarlyView.
Abstract The idea that disease is caused at the cellular level is so fundamental to us that we might forget the critical role microscopy played in generating and developing this insight. Visually identifying diseased or infected cells lays the foundation for any effort to curb human pathology.
Julien Guizetti
wiley   +1 more source