Results 151 to 160 of about 249,029 (275)
Exploring Aspartate Transcarbamoylase: A Promising Broad‐Spectrum Target for Drug Development
ChemBioChem, Volume 26, Issue 7, April 1, 2025.Pyrimidine biosynthesis is a pivotal process shared by both eukaryotes and prokaryotes. This review examines the applications and advantages of a series of inhibitors specifically designed to target aspartate transcarbamylase within the de novo biosynthetic pathway of the malarial parasite.
Siyao Chen +8 more
wiley +1 more source
Complicated vivax malaria, an often underestimated condition - Case Report
Journal of Family and Community Medicine, 2015 Malaria is a vector-borne disease that is endemic in 91 countries. South East Asia is the second most affected region in the world, with India carrying the highest burden of the disease.
Arumugam Aashish, Gopi Manigandan
doaj +1 more source
Malaria Detection and Classificaiton [PDF]
arXiv, 2020 Malaria is a disease of global concern according to the World Health Organization. Billions of people in the world are at risk of Malaria today. Microscopy is considered the gold standard for Malaria diagnosis. Microscopic assessment of blood samples requires the need of trained professionals who at times are not available in rural areas where Malaria ...
arxiv
Diagnosis and Treatment of Plasmodium vivax Malaria
American Journal of Tropical Medicine and Hygiene, 2016 The diagnosis and treatment of Plasmodium vivax malaria differs from that of Plasmodium falciparum malaria in fundamentally important ways. This article reviews the guiding principles, practices, and evidence underpinning the diagnosis and treatment of P.
J. K. Baird +6 more
semanticscholar +1 more source
Rapid Diagnostic Testing for Plasmodium vivax and Nonfalciparum Malaria in Endemic Areas [PDF]
, 2015 Clinical Question How sensitive and specific are rapid diagnostic tests (RDTs) for diagnosing Plasmodium vivax and nonfalciparum malaria in endemic areas?
Abba, Katharine +2 more
core +1 more source
Circulating Growth Differentiation Factor 15 (GDF15) in Paediatric Disease: A Systematic Review
Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 2, April 2025.ABSTRACT Background Growth Differentiation Factor 15 (GDF15), a nonspecific inflammatory marker and member of the TGF‐β superfamily, has a well‐established role in both inflammation and metabolic modulation, but lacks a comprehensive paediatric literature review.
David W. Kronenberger +3 more
wiley +1 more source
Journal of Infection and Public Health, 2016 Summary: Malaria in children is still an important public health problem in endemic areas of South-East Asia and Latin America. Certain forms of the disease, such as Plasmodium vivax severe malaria, are still neglected.
Diego A. Medina-Morales +4 more
doaj
Malaria Journal, 2012 Background Infection by Plasmodium vivax has been considered rarely threatening to life, but recent studies challenge this notion. This study documented the frequency and character of severe illness in paediatric patients admitted to a hospital in south ...
Shaikh Salma +5 more
doaj +1 more source
Malaria intensity in Colombia by regions and populations [PDF]
, 2017 Determining the distribution of disease prevalence among heterogeneous populations at the national scale is fundamental for epidemiology and public health. Here, we use a combination of methods (spatial scan statistic, topological data analysis, epidemic profile) to study measurable differences in malaria intensity by regions and populations of ...
arxiv +1 more source
Malaria Journal, 2016 BackgroundAs malaria transmission declines, it becomes more geographically focused and more likely due to asymptomatic and non-falciparum infections. To inform malaria elimination planning in the context of this changing epidemiology, local assessments ...
Herdiana Herdiana +10 more
semanticscholar +1 more source