Results 1 to 10 of about 3,657 (146)
Population pharmacokinetics of primaquine and its metabolites in African males
Background Primaquine (PQ) is the prototype 8-aminoquinoline drug, a class which targets gametocytes and hypnozoites. The World Health Organization (WHO) recommends adding a single low dose of primaquine to the standard artemisinin-based combination ...
Palang Chotsiri +12 more
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BackgroundThe countries within the Greater Mekong Region of Southeast Asia have pledged to eliminate malaria by 2030. Elimination of Plasmodium vivax malaria is challenging as it requires radical cure to prevent relapse.
April T Ansari +15 more
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Some of the next articles are maybe not open access.
Clinical Pharmacology & Therapeutics, 1964
Methemoglobin formation occurring as a toxic manifestation of primaquine was studied in volunteers to determine whether or not it is an example of genetic polymorphism. No evidence of polymorphism was found.
W K, COWAN, D A, EVANS
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Methemoglobin formation occurring as a toxic manifestation of primaquine was studied in volunteers to determine whether or not it is an example of genetic polymorphism. No evidence of polymorphism was found.
W K, COWAN, D A, EVANS
openaire +2 more sources
High dose of primaquine in primaquine resistant vivax malaria
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1994The efficacy of low dose chloroquine, characteristic pattern of relapse and the relapse rate in vivax malaria after high dose primaquine were investigated in 167 Thai patients. 87 patients were allocated at random to receive 300 mg, and 80 received 450 mg of chloroquine on the first day of admission.
D, Bunnag +7 more
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