Results 151 to 160 of about 231,969 (238)

Whole Blood Transcriptomic Analysis of Sickle Cell Trait

European Journal of Haematology, EarlyView.
ABSTRACT Sickle cell trait (SCT) is the heterozygous carrier state for the HBB missense variant which causes sickle cell disease (SCD). SCT has been associated with increased risk of venous thromboembolism and chronic kidney disease as well as alterations in clinical laboratory parameters. To investigate differential gene expression in SCT, we used RNA
Mari Johnson, Yanwei Cai, Ana Gabriela Vasconcelos, Peter Orchard, Paul L. Auer, Guillaume Lettre, Jia Wen, Nora Franceschini, Charles Kooperberg, Wei Sun, Li Hsu, Laura M. Raffield, Alex P. Reiner   +12 more
wiley   +1 more source

Community awareness and health providers' perspectives on zoonotic Plasmodium knowlesi malaria in Thailand: A mixed-methods assessment. [PDF]

PLoS Negl Trop Dis
Sripoorote P, Inthitanon N, Wattanagoon Y, Cui L, Nguitragool W, Fornace K, Sattabongkot J, Parker DM, Aung PL.   +8 more
europepmc   +1 more source

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

The FEBS Journal, EarlyView.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk, Kamil Steczkiewicz, Mariusz Radkiewicz, Paweł Link‐Lenczowski, Przemysław Surowiecki, Karolina Sztompka, Kariona A. Grabińska, Jacek K. Nowak, Liliana Surmacz   +8 more
wiley   +1 more source

Evaluating the effectiveness of insecticide-treated net use in preventing malaria among children under five: a quasi-experimental study. [PDF]

Trop Med Health
Osei KM, Adiak AA, Han W.
europepmc   +1 more source

Digital Pathology in Hematopathology: From Vision to Deployment

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Digital pathology (DP) has evolved alongside other technical advances, transforming our daily lives and diagnostic medicine. It is likely that, as in other areas of life, science, and medicine, the overall level of digitization will continue to rise, along with an increasing number of groups implementing DP.
Ryan C. Shean, Anton V. Rets
wiley   +1 more source

Agent-based simulation of seasonal malaria chemoprevention strategy in Southern Tanzania: comparing dihydroartemisinin-piperaquine with or without primaquine. [PDF]

Malar J
Mfala CT, Nyambo DG, Mwaiswelo RO, Tchuenche JM, Clemen T.   +4 more
europepmc   +1 more source

Multinational enterprises and disadvantaged communities in emerging markets: A review and theoretical framework

International Journal of Management Reviews, EarlyView.
Abstract Multinational enterprises (MNEs) face growing pressures from stakeholders to address global challenges and alleviate inequalities endured by disadvantaged communities in the regions where they operate. Given the fragmented conceptual approaches to understanding the relationships between MNEs and these communities, the complex mechanisms ...
Jayne Cathcart, Renan Oliveira, Axèle Giroud, Jorge Carneiro, Pervez Ghauri   +4 more
wiley   +1 more source

Comparative clinical transcriptome of pir genes in severe Plasmodium vivax malaria. [PDF]

PLoS Negl Trop Dis
Boopathi PA, Singh S, Roy P, Tahbildar S, Kochar SK, Kochar DK, Das A.   +6 more
europepmc   +1 more source

Resilient Biophysical Phenotype of Memory CD4+ T Cells in Long‐Lived Mice

Immunology, EarlyView.
Aging is associated with increased stiffness and reduced migratory capacity of memory CD4+ T cells; however, these biophysical declines do not persist in exceptionally long‐lived mice. Instead, long‐lived individuals preserve T cell mechanics, migration and intracellular architecture, supporting mechanical resilience as a hallmark of successful immune ...
Aldo Abarca‐Ortega, Blanca González‐Bermúdez, Judith Félix‐Escalera, Mónica González‐Sánchez, Enzo Brito, Mónica De la Fuente, Gustavo R. Plaza   +6 more
wiley   +1 more source

Climate variability and malaria incidence trends in Yumbe District, West Nile Sub-region of Uganda (2017-2021). [PDF]

Malar J
Ninsiima LR, Musiitwa R, Nanyunja Z, Muleme J, Maasaba C, Anule T, Musoke D.   +6 more
europepmc   +1 more source