Results 151 to 160 of about 522,734 (372)

MALARIA IN CHILDREN

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2012
This review is focused on childhood specific aspects of malaria, especially in resource-poor settings. We summarise the actual knowledge in the field of epidemiology, clinical presentation, diagnosis, management and prevention.These aspects are important as malaria is responsible for almost a quarter of all child death in sub-Saharan Africa.
Elena Spinelli   +1 more
openaire   +6 more sources

Hybrid Molecules as Efficient Drugs against Multidrug‐Resistant Malaria Parasites

open access: yesChemMedChem, EarlyView.
Among hybrid molecules currently developed as antimalarial drug candidates, emoquine‐1 exhibits high activity against all the multidrug‐resistant Plasmodium strains tested up to now, including artemisinin‐resistant quiescent parasites, critical parameters for promising antimalarial drugs. It is also curative in mouse malaria.
Anne Robert   +6 more
wiley   +1 more source

Cytokine expression in malaria-infected non-human primate placentas [PDF]

open access: yesM. Barasa, Z.W. Ng'ang'a et al. Cytokine expression in malaria-infected non-human primate placentas. Open Veterinary Journal, (2012), Vol. 2: 58-64, 2012
Malaria parasites are known to mediate the induction of inflammatory immune responses at the maternal-foetal interface during placental malaria (PM) leading to adverse consequences like pre-term deliveries and abortions. Immunological events that take place within the malaria-infected placental micro-environment leading to retarded foetal growth and ...
arxiv  

Dose Determinations at Drug Approval Reviews: FDA‐Approved Drugs in Past 5 Years

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Drug dose appropriateness is one of the most discussed issues in regulatory reviews. We analyzed dose determinations during Food and Drug Administration (FDA) drug reviews to determine whether there were changes between the proposed and approved doses of new molecular entities (NMEs), including cases where postmarketing dose‐finding studies were ...
Sachiko Mita, Shunsuke Ono
wiley   +1 more source

Malaria elimination and the need for intensive inter-country cooperation: a critical evaluation of regional technical co-operation in Southern Africa

open access: yesMalaria Journal
Background Malaria elimination requires closely co-ordinated action between neighbouring countries. In Southern Africa several countries have reduced malaria to low levels, but the goal of elimination has eluded them thus far.
Chadwick H. Sikaala   +9 more
doaj   +1 more source

A comparative stochastic and deterministic study of a class of epidemic dynamic models for malaria: exploring the impacts of noise on eradication and persistence of disease [PDF]

open access: yesarXiv, 2018
A comparative stochastic and deterministic study of a family of SEIRS epidemic dynamic models for malaria is presented. The family type is determined by the qualitative behavior of the nonlinear incidence rates of the disease. Furthermore, the malaria models exhibit three random delays:- two of the delays represent the incubation periods of the disease
arxiv  

STUDIES ON THE CHEMOTHERAPY OF THE HUMAN MALARIAS. VI. THE PHYSIOLOGICAL DISPOSITION, ANTIMALARIAL ACTIVITY, AND TOXICITY OF SEVERAL DERIVATIVES OF 4-AMINOQUINOLINE 12 [PDF]

open access: bronze, 1948
Robert W. Berliner   +8 more
openalex   +1 more source

Evaluation of cervical cancer screening strategies in women living with HIV in Thailand

open access: yes
Cancer Communications, EarlyView.
Patumrat Sripan   +10 more
wiley   +1 more source

Rethinking Chlorine: Essential Chemical or Replaceable Risk?

open access: yesChemSusChem, Accepted Article.
This review critically examines the dual nature of chlorine as both an indispensable base chemical and a potential risk. Chlorine and its by‐product hydrogen chloride play essential roles in the production of pharmaceuticals, plastics, agrochemicals, and disinfectants.
Johannes Schwan   +6 more
wiley   +1 more source

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