ON A CONVENIENT TERMINOLOGY FOR THE VARIOUS STAGES OF THE MALARIA PARASITE [PDF]
E. Ray Lankester
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This review is focused on childhood specific aspects of malaria, especially in resource-poor settings. We summarise the actual knowledge in the field of epidemiology, clinical presentation, diagnosis, management and prevention.These aspects are important as malaria is responsible for almost a quarter of all child death in sub-Saharan Africa.
Elena Spinelli+1 more
openaire +6 more sources
Hybrid Molecules as Efficient Drugs against Multidrug‐Resistant Malaria Parasites
Among hybrid molecules currently developed as antimalarial drug candidates, emoquine‐1 exhibits high activity against all the multidrug‐resistant Plasmodium strains tested up to now, including artemisinin‐resistant quiescent parasites, critical parameters for promising antimalarial drugs. It is also curative in mouse malaria.
Anne Robert+6 more
wiley +1 more source
Cytokine expression in malaria-infected non-human primate placentas [PDF]
Malaria parasites are known to mediate the induction of inflammatory immune responses at the maternal-foetal interface during placental malaria (PM) leading to adverse consequences like pre-term deliveries and abortions. Immunological events that take place within the malaria-infected placental micro-environment leading to retarded foetal growth and ...
arxiv
Dose Determinations at Drug Approval Reviews: FDA‐Approved Drugs in Past 5 Years
Drug dose appropriateness is one of the most discussed issues in regulatory reviews. We analyzed dose determinations during Food and Drug Administration (FDA) drug reviews to determine whether there were changes between the proposed and approved doses of new molecular entities (NMEs), including cases where postmarketing dose‐finding studies were ...
Sachiko Mita, Shunsuke Ono
wiley +1 more source
Background Malaria elimination requires closely co-ordinated action between neighbouring countries. In Southern Africa several countries have reduced malaria to low levels, but the goal of elimination has eluded them thus far.
Chadwick H. Sikaala+9 more
doaj +1 more source
A comparative stochastic and deterministic study of a class of epidemic dynamic models for malaria: exploring the impacts of noise on eradication and persistence of disease [PDF]
A comparative stochastic and deterministic study of a family of SEIRS epidemic dynamic models for malaria is presented. The family type is determined by the qualitative behavior of the nonlinear incidence rates of the disease. Furthermore, the malaria models exhibit three random delays:- two of the delays represent the incubation periods of the disease
arxiv
STUDIES ON THE CHEMOTHERAPY OF THE HUMAN MALARIAS. VI. THE PHYSIOLOGICAL DISPOSITION, ANTIMALARIAL ACTIVITY, AND TOXICITY OF SEVERAL DERIVATIVES OF 4-AMINOQUINOLINE 12 [PDF]
Robert W. Berliner+8 more
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Evaluation of cervical cancer screening strategies in women living with HIV in Thailand
Cancer Communications, EarlyView.
Patumrat Sripan+10 more
wiley +1 more source
Rethinking Chlorine: Essential Chemical or Replaceable Risk?
This review critically examines the dual nature of chlorine as both an indispensable base chemical and a potential risk. Chlorine and its by‐product hydrogen chloride play essential roles in the production of pharmaceuticals, plastics, agrochemicals, and disinfectants.
Johannes Schwan+6 more
wiley +1 more source