Results 171 to 180 of about 697,481 (397)

Accelerating the prioritisation of plant species with underexplored medicinal potential: The pm4mp (Phylogenetic Methods for Medicinal Plants) R package

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Medicinal plants used in ethnobotanical traditions to treat or prevent diseases have gained renewed interest for their largely untapped potential in drug discovery. In this study, we developed and tested novel methods to prioritise plant species based on their unexplored medicinal potential. By enabling researchers to target the most promising species,
Giovanni Zecca   +3 more
wiley   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

open access: yesPrecision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva   +10 more
wiley   +1 more source

Commercial permethrin elicits chemoreceptive responses on different Anopheles gambiae sensory appendages

open access: yesPest Management Science, EarlyView.
Anopheles gambiae mosquitoes exhibit takeoff responses when presented to commercial permethrin headspace. This product elicits electrophysiological activity in the antennae and tarsi. However, only the chemical information acquired from the tarsi plays a major role in the observed behavioral response.
Sassan S Kambou   +4 more
wiley   +1 more source

Seasonal climate patterns and their impact on mosquito net use in Nigeria: evidence from repeated surveys

open access: yesMalaria Journal
Consistent use of insecticide-treated nets (ITNs) for malaria prevention has been a challenge undermining the intervention’s effectiveness. Perceptions of heat and absence of mosquitoes are among the reasons cited for non-use of ITN in populations with ...
Tarekegn A. Abeku   +3 more
doaj   +1 more source

Malaria [PDF]

open access: yesBMJ, 2011
Mirza, D. M., Hashim, M. J., Sheikh, A.
openaire   +2 more sources

Long‐term impact of exposure to Royal Guard, a pyriproxyfen‐based bed net, on pyrethroid‐resistant malaria vectors from Cameroon using DNA‐based metabolic resistance markers

open access: yesPest Management Science, Volume 81, Issue 4, Page 2165-2180, April 2025.
We used recently detected P450 DNA‐based markers of pyrethroid resistance in both Anopheles funestus and Anopheles gambiae to demonstrate that although pyrethroid‐resistant mosquitoes have higher ability to survive and live longer after exposure to Royal Guard, this net significantly affects their lifespan, blood feeding ability and interestingly ...
Emilie S Ngongang‐Yipmo   +8 more
wiley   +1 more source

Comparison of Two Rapid Diagnostic Tests with Conventional Microscopy for Detection of Malaria parasites

open access: diamond, 2017
Eman Shoeib   +99 more
openalex   +1 more source

Exploring existing malaria services and the feasibility of implementing community engagement approaches amongst conflict-affected communities in Cameroon: a qualitative study

open access: yesMalaria Journal
Background Cameroon is one of the countries with the highest burden of malaria. Since 2018, there has been an ongoing conflict in the country, which has reduced access to healthcare for populations in affected regions, and little is known about the ...
Margaret Ebob Besem E.O   +19 more
doaj   +1 more source

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