Results 201 to 210 of about 361,983 (304)

CDC Operational Guidance for Investigating Locally Acquired Mosquito-Transmitted Malaria - United States, 2026. [PDF]

MMWR Recomm Rep
Ranadive N, Barratt JLN, Dotson EM, Gimnig JE, Lenhart AE, Levine RS, Mace KE, McElroy PD, Raphael BH, Sayre D, Steinhardt LC, Sutcliffe AC, Williams SG, Ridpath AD.   +13 more
europepmc   +1 more source

Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders

The FEBS Journal, EarlyView.
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo, Bastien Morlet, Luc Negroni, Orsolya Mózner, Balázs Sarkadi, Gilles Travé, Gergo Gogl   +6 more
wiley   +1 more source

Knowledge, attitudes and practices towards uncomplicated malaria management and LLIN use in Kumba and Muyuka, Cameroon: a cross-sectional study. [PDF]

BMJ Public Health
Tongwa DZ, Ndim MCF, Mbiziwoh TP, Chi YM, Tatah CA, Ngome FN, Kofon JP, Elad PCK, Tsobgni SPK, Mbonigaba E, Nyanjoh EM, Tassang AN, Cho FN.   +12 more
europepmc   +1 more source

PEG400 regulates Falcipain 2 activity through an allosteric mechanism

The FEBS Journal, EarlyView.
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath, Subhoja Chakraborty, Sampa Biswas   +2 more
wiley   +1 more source

Immune modulation and treatment outcomes among patients with malaria and typhoid fever in Yaoundé, Cameroon: a comparative analysis of inflammatory responses. [PDF]

BMJ Public Health
Netongo PM, Bin Eric M, Tchoupe KEB, Nzuno MMC, Kamdem SD, Tchoutang AM, Neba FR, Buri BD, Tepa A, Numfor NL, Ngum NL, Akindeh MN, Mbacham FW.   +12 more
europepmc   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

Leptospirosis is associated with severity, increased resource utilization, and mortality among acute febrile illnesses from Karnataka, Southwestern India. [PDF]

Ann Med
Panjabi GR, Joseph G, Saravu K.
europepmc   +1 more source

Seventh Åland Island Meeting on von Willebrand Disease

Haemophilia, EarlyView.
ABSTRACT Introduction The seventh Åland Island Meeting on von Willebrand Disease (VWD) was held on the Åland archipelago in Finland, from 26 to 28 September 2024. Aim The meeting brought together experts in the field of VWD from around the world to share the latest advances and knowledge in VWD.
Riitta Lassila, Ruben Bierings, Nathan T. Connell, Fernando F. Corrales‐Medina, Augusto B. Federici, Veronica H. Flood, Floor Heubel‐Moenen, Jill M. Johnsen, Geoffrey Kuppens, Davide Matino, Carolyn Millar, Ingmar Schoen, Anish Sharda, Robert F. Sidonio Jr, Alok Srivastava, Timea Szanto, Angela C. Weyand, Erik Berntorp   +17 more
wiley   +1 more source

Ecology of Malaria Mortality: A Spatiotemporal Mapping Approach. [PDF]

Am J Biol Anthropol
Cooke A, Brickley MB.
europepmc   +1 more source

Death after discharge among children living with HIV admitted with suspected sepsis in Uganda: A secondary analysis of two prospective observational studies

HIV Medicine, EarlyView.
Abstract Background Children living with HIV in low‐income countries contribute disproportionately to death after hospital discharge. This study investigates the effect of HIV on post‐discharge mortality and readmission by exploring a wide range of clinical, maternal and socioeconomic variables.
O. Mackenzie, C. Zhang, N. Kissoon, N. Ford, N. Sugandhi, E. Kumbakumba, J. Kabakyenga, C. Komugisha, N. K. Mugisha, M. O. Wiens   +9 more
wiley   +1 more source