Results 51 to 60 of about 44,517 (310)

Operational strategies of anti-malarial drug campaigns for malaria elimination in Zambia's southern province: a simulation study [PDF]

, 2016
BACKGROUND: Malaria elimination requires reducing both the potential of mosquitoes to transmit parasites to humans and humans to transmit parasites to mosquitoes. To achieve this goal in Southern province, Zambia a mass test and treat (MTAT) campaign was
Miller, John M., Erin M. Stuckey, Rick Steketee, Stuckey, Erin M., Chitnis, Nakul, Steketee, Rick, Megan Littrell, Nakul Chitnis, Littrell, Megan, John M. Miller   +9 more
core   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Malaria elimination and the need for intensive inter-country cooperation: a critical evaluation of regional technical co-operation in Southern Africa

Malaria Journal
Background Malaria elimination requires closely co-ordinated action between neighbouring countries. In Southern Africa several countries have reduced malaria to low levels, but the goal of elimination has eluded them thus far.
Chadwick H. Sikaala, Bongani Dlamini, Alphart Lungu, Phelele Fakudze, Mukosha Chisenga, Chishala Lukwesa Siame, Nyasha Mwendera, Dumisani Shaba, John M. Chimumbwa, Immo Kleinschmidt   +9 more
doaj   +1 more source

En-route to the ‘elimination’ of genotypic chloroquine resistance in Western and Southern Zambia, 14 years after chloroquine withdrawal

Malaria Journal, 2019
Background Anti-malarial resistance is, and continues to be a significant challenge in the fight against malaria and a threat to achieving malaria elimination.
Lungowe Sitali, Mulenga C. Mwenda, John M. Miller, Daniel J. Bridges, Moonga B. Hawela, Elizabeth Chizema-Kawesha, James Chipeta, Bernt Lindtjørn   +7 more
doaj   +1 more source

The use of spatial and genetic tools to assess Plasmodium falciparum transmission in Lusaka, Zambia between 2011 and 2015

Malaria Journal, 2020
Background Zambia has set itself the ambitious target of eliminating malaria by 2021. To continue tracking transmission to zero, new interventions, tools and approaches are required.
Daniel J. Bridges, Sandra Chishimba, Mulenga Mwenda, Anna M. Winters, Erik Slawsky, Brenda Mambwe, Conceptor Mulube, Kelly M. Searle, Aves Hakalima, Roy Mwenechanya, David A. Larsen   +10 more
doaj   +1 more source

A world malaria map: Plasmodium falciparum endemicity in 2007 [PDF]

, 2009
BACKGROUND: Efficient allocation of resources to intervene against malaria requires a detailed understanding of the contemporary spatial distribution of malaria risk. It is exactly 40 y since the last global map of malaria endemicity was published.
Guerra, C.A., David L Smith, Guerra, Carlos A, Kabaria, Caroline W., Smith, David L., Peter W Gething, Guerra, CA, Tatem, AJ, Snow, Robert, Elyazar, I.R., Noor, AM, Elyazar, Iqbal R. F., Hay, S.I., Hay, Simon, Caroline W Kabaria, Moyeed, Rana A, Noor, Abdisalan M., Snow, Robert W, Tatem, A.J., Tatem, Andrew J, Snow, RW, Robert W Snow, Snow, Robert W., Moyeed, R. A., Hay, Simon I., Guerra, Carlos A., Abdisalan M Noor, Kabaria, C.W., Manh, B.H., Patil, AP, Anand P Patil, Kabaria, Caroline W, Elyazar, IR, Andrew J Tatem, Noor, Abdisalan M, Patil, A.P., Brooker, Simon, Smith, David L, Hay, Simon I, Gething, Peter W, Bui H Manh, Hay, SI, Rana A Moyeed, Manh, BH, Gething, Peter W., Patil, Anand P, Manh, Bui H, Brooker, S., Carlos A Guerra, Smith, DL, Iqbal R. F Elyazar, Tatem, Andrew J., Moyeed, RA, Smith, D.L., Kabaria, CW, Moyeed, Rana A., Iqbal R F Elyazar, Gething, P.W., Gething, PW, Noor, A.M., Brooker, S, Elyazar, Iqbal RF, Simon Brooker, Patil, Anand P., Snow, R.W., Simon I Hay, Manh, Bui H.   +66 more
core   +1 more source

Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies

Advanced Science, EarlyView.
In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang, Xinxin Zou, Jiansong Zhou, Qinmiao Sun, Dahua Chen   +4 more
wiley   +1 more source

Quality of inpatient test-and-treat malaria case-management in public and private hospitals in Kano State, Nigeria

Malaria Journal
Background Compliance with evidence-based treatment guidelines, supported by quality-assured parasitological diagnosis, is the mainstay of malaria case-management in Nigeria.
Dawit Getachew, Nnenna Ogbulafor, Emmanuel Shekarau, Babangida Musa, Abdullahi Yusuf, Safiyanu Haruna, Oladipo O. Oladosu, Olusola Oresanya, Kolawole Maxwell, Dejan Zurovac   +9 more
doaj   +1 more source

Using the Entomological Inoculation Rate to Assess the Impact of Vector Control on Malaria Parasite Transmission and Elimination. [PDF]

, 2010
Prior studies have shown that annual entomological inoculation rates (EIRs) must be reduced to less than one to substantially reduce the prevalence of malaria infection.
Ayesha M Shaukat, Shaukat, Ayesha M, Breman Joel G, Shaukat Ayesha M, McKenzie, F Ellis, McKenzie F Ellis, Joel G Breman, F Ellis McKenzie, Breman, Joel G   +8 more
core   +1 more source

Artificial Intelligence‐Driven Network Pharmacology: A Methodological Paradigm Shift Bridging Traditional Wisdom and Modern Science

Advanced Intelligent Discovery, EarlyView.
Artificial intelligence is redefining network pharmacology (NP). By integrating knowledge graph engineering, geometric deep learning, multiomics anchoring, and generative reasoning, AI‐driven NP (AI‐NP) transforms static target mapping into dynamic, predictive modeling.
Cong Wang, Sile Hu, Rigahai Ji, Riguna A, Siqige Hao, Ma Zhuo, Yi‐Hung Chen, Bisihalatu Hu, Ulana Bai, Xigui Hada   +9 more
wiley   +1 more source