Results 151 to 160 of about 92,873 (283)
Genome‐Guided Discovery of Antimalarial 4‐Amino‐2,4‐Pentadienoate‐Containing Cyclolipodepsipeptides
Angewandte Chemie, Volume 138, Issue 18, 27 April 2026.Halogenated and glycosylated 4‐amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) exhibit potent antiplasmodial activity (IC50 = 25–161 nM) against drug‐sensitive and resistant Plasmodium falciparum strains. ABSTRACT 4‐Amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) represent a structurally distinctive family of ...
Hartono Candra +10 more
wiley +2 more sources
Public health reforms and the mortality decline in nineteenth‐century Italy
The Economic History Review, Volume 79, Issue 2, Page 527-554, May 2026.Abstract This study examines the impact of Italy's 1887–8 health reforms on mortality, contributing to the historical debate on the state's role in Europe's health transition. Leveraging event‐study‐style difference‐in‐differences approach, we assess the effectiveness of the Crispi–Pagliani reforms, which strengthened public health governance and ...
Francesco Maria Salvatore Fiore Melacrinis +1 more
wiley +1 more source
The disappearance of malaria from Denmark, 1862–1900
The Economic History Review, Volume 79, Issue 2, Page 555-574, May 2026.Abstract The reason for malaria's disappearance from northwestern Europe in the early twentieth century has long been discussed but remains an unresolved conundrum. This is partially due to a previous focus on the early modern era, and partially because various theories have never been tested against each other.
Mathias Mølbak Ingholt +3 more
wiley +1 more source
A Geographical Location Model for Targeted Implementation of Lure-and-Kill Strategies Against Disease-Transmitting Mosquitoes in Rural Areas [PDF]
, 2012 Outdoor devices for luring and killing disease-transmitting mosquitoes have been proposed as potential com- plementary interventions alongside existing intra-domiciliary methods namely insecticide treated nets and house spraying with residual ...
Lwetoijera, Dickson W. +3 more
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Ancestral Irrigation and Women's Political Empowerment
Kyklos, Volume 79, Issue 2, Page 377-398, May 2026.ABSTRACT This paper advances the hypothesis and establishes empirically that the adoption of irrigation agriculture during the preindustrial period is a predictor of contemporary cross‐country variation in women's political empowerment. Countries whose populations historically relied on irrigation agriculture as their primary subsistence mode tend to ...
Roberto Ezcurra
wiley +1 more source
Plant Biotechnology Journal, Volume 24, Issue 5, Page 2826-2842, May 2026.ABSTRACT Efficient viral proliferation within the host is a critical step in pathogenicity and requires adenosine triphosphate (ATP). The replication, movement and immune evasion of many plant viruses within their hosts are associated with phase separation (PS)‐derived aggregates formed by viral components.
Guangcheng Zu +8 more
wiley +1 more source
Quantifying Mozambique's Peace Dividend: An Application of the Synthetic Control Method
Review of Development Economics, Volume 30, Issue 2, Page 847-864, May 2026.ABSTRACT Using the synthetic control method and data from 20 African countries, this study quantifies the peace dividend in Mozambique, a country that experienced over 15 years of civil war. More specifically, we use data from 1977 to 2018 to investigate whether the end of the civil war in Mozambique in 1992 brought significant benefits to the country ...
Tendai Gwatidzo, Aldo Sitoe, Busani Moyo
wiley +1 more source
Aid to Fight AIDS: An Empirical Analysis of HIV‐Specific Development Aid Effectiveness
Scottish Journal of Political Economy, Volume 73, Issue 2, May 2026.ABSTRACT Using an excludable instrument for HIV‐specific aid, we investigate its effectiveness on HIV outcomes viz., prevalence and death rates. We theorize that HIV‐specific aid fills the funding gap that prevents governments from committing adequate resources to effectively address the epidemic.
Derek Nolan +1 more
wiley +1 more source
Structure‐ and Ligand‐Based Discovery of Novel 3‐Chymotrypsin‐Like Protease Nonpeptidomimetic Hits
ChemMedChem, Volume 21, Issue 7, 14 April 2026.A multistep virtual screening cascade, integrating shape‐based, ensemble docking, and quantitative structure–activity relationship (QSAR) models, was employed to screen 1.5 million compounds. This funnel identified a novel 3‐chymotrypsin‐like protease (3CLpro) inhibitor, LabMol‐499, which was experimentally validated using a Förster Resonance Energy ...
Sabrina Silva‐Mendonça +14 more
wiley +1 more source