Saccharomyces cerevisiae malate dehydrogenase Mdh1p lacking mitochondrial targeting signal can be re-localized to peroxisomes. [PDF]
Chan C +4 more
europepmc +1 more source
Isolation of the cytoplasmic form of malate dehydrogenase from honey bee (Apis mellifera) larvae
Thomas P. Snyder +2 more
openalex +2 more sources
Elements and roadmap for interactive molecular graphics and modeling “in the Holodeck”
Abstract Molecular graphics have been instrumental in advancing chemistry, drug discovery, materials science and structural biology, enabling visualization of molecular systems from static images to dynamic web displays and immersive platforms. While effective visualization is largely a solved problem, in this perspective we argue that the next ...
Adrian J. Mulholland, Luciano A. Abriata
wiley +1 more source
Defined metabolic states shape T cell fate and function across culture conditions. [PDF]
Sylvester K +4 more
europepmc +1 more source
This work presents the physiological exploration of the halo‐alkaliphilic, carboxydotrophic acetogen bacterium MD4. In contrast to well‐characterised neutrophilic and slightly acidophilic acetogenic carboxydotrophs, this work shows an important role for formate production, instead of ethanol, as a redox exhaust mechanism in alkaline conditions ...
Martijn Diender +5 more
wiley +1 more source
Interplay between malic enzyme 2, de novo serine synthesis, and the malate-aspartate shuttle drives metabolic adaptation in triple-negative breast cancer. [PDF]
Jeon JH +21 more
europepmc +1 more source
Lifespan‐Extending Endogenous Metabolites
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley +1 more source
Exploring Metabolic Disruption and Redox Modulation by Senna Leaf Extracts Induces Mortality in the Zoonotic Parasite <i>Hymenolepis diminuta</i>. [PDF]
Roy S, Lyndem LM.
europepmc +1 more source

