Results 311 to 320 of about 151,333 (388)

Elements and roadmap for interactive molecular graphics and modeling “in the Holodeck”

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract Molecular graphics have been instrumental in advancing chemistry, drug discovery, materials science and structural biology, enabling visualization of molecular systems from static images to dynamic web displays and immersive platforms. While effective visualization is largely a solved problem, in this perspective we argue that the next ...
Adrian J. Mulholland, Luciano A. Abriata
wiley   +1 more source

Defined metabolic states shape T cell fate and function across culture conditions. [PDF]

open access: yesFront Immunol
Sylvester K   +4 more
europepmc   +1 more source

Carboxydotrophic Acetogenesis in Alkaline Conditions Results in Transient Formate Production by the Halo‐Alkaliphilic Acetogen Haloacetibacter carboxydivorans Gen. Nov. sp. Nov

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
This work presents the physiological exploration of the halo‐alkaliphilic, carboxydotrophic acetogen bacterium MD4. In contrast to well‐characterised neutrophilic and slightly acidophilic acetogenic carboxydotrophs, this work shows an important role for formate production, instead of ethanol, as a redox exhaust mechanism in alkaline conditions ...
Martijn Diender   +5 more
wiley   +1 more source

Interplay between malic enzyme 2, de novo serine synthesis, and the malate-aspartate shuttle drives metabolic adaptation in triple-negative breast cancer. [PDF]

open access: yesCancer Metab
Jeon JH   +21 more
europepmc   +1 more source

Lifespan‐Extending Endogenous Metabolites

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley   +1 more source

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