Results 61 to 70 of about 76,469 (250)

Transient Carbon Reserves in Barley: Malate, Sucrose and Starch Are the Main Players, Their Quantitative Involvement Being Light Intensity Dependant

open access: yesFrontiers in Plant Science, 2020
Under natural environment plants experience different light intensities which can affect photosynthesis and consequently the availability of carbohydrates for daytime growth and their transient storage to supply night growth.
Kallyne A. Barros   +6 more
doaj   +1 more source

Chemoreactomic analysis of citrulline malate molecules

open access: yes, 2017
Citrulline malate that is essential for the biosynthesis of arginine promotes dehydration of ammonium endotoxins, by participating in the urea cycle. The indications for the use of citrulline malate are functional asthenia, asthenic syndrome, overfatigue,
K. V. Rudakov   +4 more
core   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

open access: yesAdvanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He   +7 more
wiley   +1 more source

Conjugated Polymer‐Microbe Interactions Trigger Regulatory Reprogramming for Enhanced Bioelectrocatalysis

open access: yesAdvanced Science, EarlyView.
Conjugated polymer‐supported bioelectrochemical systems are shown to enhance microbial electrosynthesis by triggering coordinated electrochemical, transcriptional, post‐transcriptional (sRNA), metabolic, and protein‐level responses. Integrated multi‐omics and electrochemical analyses reveal selective physiological remodeling associated with improved ...
David Ohayon   +8 more
wiley   +1 more source

The logics of metabolic regulation in bacteria challenges biosensor-based metabolic engineering

open access: yesMicrobial Cell, 2017
Synthetic Biology (SB) aims at the rational design and engineering of novel biological functions and systems. By facilitating the engineering of living organisms, SB promises to facilitate the development of many new applications for health ...
Matthieu Jules
doaj   +1 more source

Simulation of malate and citrate isotopologues and their dependence on Citrate-Malate Shuttle (CMS) activity or anaplerosis

open access: yes, 2022
This dataset contains supplementary data to the article entitled: “Krebs Takes a Turn at Cell Differentiation”, by Stanislaw Deja, Peter Crawford and Shawn Burgess.
Deja, S (via Mendeley Data)
core   +1 more source

Glutaminolysis Blockade‐Empowered Bimodal Nanodepot for Spatially Complementary Sono‐Thermal Ablation via PANoptosis and STING Activation Against Large Tumors

open access: yesAdvanced Science, EarlyView.
An injectable bimodal TCPD nanodepot disrupts glutaminolysis and TCA metabolism, sensitizing large tumors to spatially complementary sono‐thermal ablation for complete treatment coverage. This intervention induces mitochondrial and endoplasmic reticulum dysfunction, genotoxicity, and NAD+ depletion, converging to trigger PANoptosome assembly and ...
Yi‐Ming Liu   +10 more
wiley   +1 more source

Malate-Based Biodegradable Scaffolds Activate Cellular Energetic Metabolism for Accelerated Wound Healing

open access: yes
The latest advancements in cellular bioenergetics have revealed the potential of transferring chemical energy to biological energy for therapeutic applications.
Zhihui Lu (9324671)   +7 more
core   +1 more source

Lactate Signal: Modulator of Cellular Energy Production and Anabolism

open access: yesAdvanced Science, EarlyView.
Compartmentalized lactate signaling provides a spatial framework for understanding how lactate‐rich states are generated, transported, sensed, and translated into biological outputs. This Review integrates extracellular, cytosolic, mitochondrial‐associated, and nuclear lactate mechanisms to explain how lactate shapes metabolic adaptation, immune ...
Han Wang, Si‐Yuan Yang, Wei Xu
wiley   +1 more source

Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome

open access: yesAnnals of Neurology, EarlyView.
Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca   +24 more
wiley   +1 more source

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