Results 201 to 210 of about 74,420 (312)

Comprehensive Analysis of Malate Accumulation in Peaches in Response to Cold Stress Based on Transcriptomics

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
This study explored malate‐accumulation mechanisms in “Hujingmilu” peaches under different storage conditions. Low temperature (LT) delayed firmness decline and maintained higher malate. Transcriptomics showed malate biosynthetic genes weakly correlate with malate levels, while proton pump and transporter genes were up‐regulated under LT.
Hongfang Cai   +6 more
wiley   +1 more source

A fragment-based approach identifies an allosteric pocket that impacts malate dehydrogenase activity. [PDF]

open access: yesCommun Biol, 2021
Reyes Romero A   +11 more
europepmc   +1 more source

Enzyme response to thyrotoxicosis and hypothyroidism in human liver and muscle [PDF]

open access: yes, 1972
Bachmaier, B.   +5 more
core  

C9orf72 Repeat Expansion Induces Metabolic Dysfunction in Human iPSC‐Derived Microglia and Modulates Glial‐Neuronal Crosstalk

open access: yesGlia, Volume 74, Issue 1, January 2026.
C9orf72 microglia display heightened glycolysis and oxidative stress, driving astrocytic reprogramming that impacts motor neurons. iPSC tricultures uncover key glial–neuronal interactions in C9orf72 pathology. ABSTRACT The C9orf72 hexanucleotide repeat expansion mutation is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and ...
Marika Mearelli   +12 more
wiley   +1 more source

Energy Metabolism Under Stress: Late‐Stage Leigh Syndrome Reveals Profound Cardiometabolic Perturbations in Ndufs4 KO Mice

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
Cardiac bioenergetic and metabolic perturbations in late‐stage Leigh syndrome. Whole‐body NDUFS4 loss severely impairs cardiac complex I activity and respiration, shifting reliance to complex II and reducing glycolytic, TCA, and amino acid‐derived energy‐generating substrates in the heart.
Karin Terburgh   +2 more
wiley   +1 more source

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