Results 81 to 90 of about 74,420 (312)

Aggregation states of mitochondrial malate dehydrogenase [PDF]

Protein Science, 1998
AbstractThe oligomeric state of fluorescein‐labeled mitochondrial malate dehydrogenase (L‐malate NAD+ oxidoreductase; mMDH; EC 1.1.1.37), as a function of protein concentration, has been examined using steady‐state and dynamic polarization methodologies. A “global” rotational relaxation time of 103 ± 7 ns was found for micromolar concentrations of mMDH‐
S A, Sánchez, T L, Hazlett, J E, Brunet, D M, Jameson   +3 more
openaire   +2 more sources

Bottom‐up Strategies for Generating Polymer Protocells That Mimic Cellular Communication

Chemistry – A European Journal, EarlyView.
This review focuses on polymeric protocells produced using a bottom‐up approach. Polymer‐based assemblies guarantee stability and designability by adjusting the properties of the amphiphilic copolymers used. The review covers protocell architectures, production, and their intra‐ and intercellular communication mechanisms.
Gloria Saorin, Xinan Huang, Voichita Mihali, Cornelia G. Palivan   +3 more
wiley   +1 more source

Engineering of Escherichia coli for Krebs cycle-dependent production of malic acid

Microbial Cell Factories, 2018
Background Malate is a C4-dicarboxylic acid widely used as an acidulant in the food and beverage industry. Rational engineering has been performed in the past for the development of microbial strains capable of efficient production of this metabolite ...
Debora Trichez, Clément Auriol, Audrey Baylac, Romain Irague, Clémentine Dressaire, Marc Carnicer-Heras, Stéphanie Heux, Jean Marie François, Thomas Walther   +8 more
doaj   +1 more source

The pathogen Moniliophthora perniciosa promotes differential proteomic modulation of cacao genotypes with contrasting resistance to witches´ broom disease [PDF]

, 2020
Background: Witches' broom disease (WBD) of cacao (Theobroma cacao L.), caused by Moniliophthora perniciosa, is the most important limiting factor for the cacao production in Brazil.
Correa, Stephany Cristiane, Cruz dos Santos, Everton, Gramacho, Karina Peres, Micheli, Fabienne, Pirovani, Carlos Priminho   +4 more
core   +1 more source

Myocardial inflammation is associated with impaired mitochondrial oxidative capacity in ischaemic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1246-1255, April 2025.
Abstract Aims Myocardial inflammation and impaired mitochondrial oxidative capacity are hallmarks of heart failure (HF) pathophysiology. The extent of myocardial inflammation in patients suffering from ischaemic cardiomyopathy (ICM) or dilated cardiomyopathy (DCM) and its association with mitochondrial energy metabolism are unknown.
Julius Borger, Elric Zweck, Constanze Moos, Patrick Horn, Fabian Voß, Heinz‐Peter Schultheiss, Jacob Eifer Møller, Udo Boeken, Hug Aubin, Artur Lichtenberg, Malte Kelm, Michael Roden, Amin Polzin, Ralf Westenfeld, Julia Szendroedi, Daniel Scheiber   +15 more
wiley   +1 more source

Gain of interaction of ALS-linked G93A superoxide dismutase with cytosolic malate dehydrogenase

Neurobiology of Disease, 2008
Protein interactions of the Amyotrophic Lateral Sclerosis (ALS)-linked copper–zinc superoxide dismutase (hSOD1) G93A mutation were studied using a fluorescence resonance energy transfer (FRET) based screening system.
Yael Mali, Nava Zisapels
doaj   +1 more source

A novel mutation in NDUFB11 unveils a new clinical phenotype associated with lactic acidosis and sideroblastic anemia [PDF]

, 2017
NDUFB11, a component of mitochondrial complex I, is a relatively small integral membrane protein, belonging to the 'supernumerary' group of subunits, but proved to be absolutely essential for the assembly of an active complex I.
Bertini, Enrico, Bianchi, Marzia, Carrozzo, Rosalba, Christodoulou, John, Di Nottia, Michela, Diodato, Daria, Dionisi Vico, Carlo, Francisci, Silvia, Gelmetti, Vania, Guo, Yiran, Lucarelli, Barbarella, Martinelli, Diego, Montanari, Arianna, Niceta, Marcello, Piemonte, Fiorella, Riley, Lisa, Rizza, Teresa, Sorrentino, Francesco, Tartaglia, Marco, Torraco, Alessandra, Valente, Enza Maria, Verrigni, Daniela   +21 more
core   +2 more sources

An experimental point of view on hydration/solvation in halophilic proteins

Frontiers in Microbiology, 2014
Protein-solvent interactions govern the behaviour of proteins isolated from extreme halophiles. In this work, we compared the solvent envelopes of two orthologous tetrameric malate dehydrogenases from halophilic and non-halophilic bacteria.
Romain eTalon, Romain eTalon, Romain eTalon, Nicolas eCoquelle, Nicolas eCoquelle, Nicolas eCoquelle, Dominique eMadern, Dominique eMadern, Dominique eMadern, Eric eGirard, Eric eGirard, Eric eGirard   +11 more
doaj   +1 more source

Characterisation of components and mechanisms involved in redox-regulation of protein import into chloroplasts [PDF]

, 2009
The vast majority of chloroplast proteins is encoded in the nucleus and thus has to be posttranslationally imported into the organelle, a process that is facilitated by two multimeric protein machineries, the Toc and Tic complexes (translocon at the ...
Stengel, Anna
core  

Two NAD-linked redox shuttles maintain the peroxisomal redox balance in Saccharomyces cerevisiae [PDF]

, 2017
In Saccharomyces cerevisiae, peroxisomes are the sole site of fatty acid β-oxidation. During this process, NAD(+) is reduced to NADH. When cells are grown on oleate medium, peroxisomal NADH is reoxidised to NAD(+) by malate dehydrogenase (Mdh3p) and ...
AL Goldstein, AM Motley, AM Motley, AW Gao, BM Bakker, C Ebikeme, CW Roermund van, CW Roermund van, D Effelsberg, DH Williamson, E Baumgart, FR Opperdoes, GB McClelland, H Xu, HR Waterham, I Yofe, K Bernhardt, M Veenhuis, ML Guther, NA Al-Saryi, PA Murphy, R Breitling, R Gee, RD Gietz, S Jung, S Kumar, S Wiese, SJ Gould, T Gronemeyer, TL Orr-Weaver, VD Antonenkov, VD Antonenkov, WF Visser, WK Huh   +33 more
core   +3 more sources