Results 131 to 140 of about 321,356 (325)

Tributyltin (TBT) biodegradation induces oxidative stress of Cunninghamella echinulata [PDF]

open access: yes, 2016
Tributyltin (TBT) is one of the most deleterious compounds introduced into natural environment by humans. The ability of Cunninghamella echinulata to degrade tributyltin (TBT) (5 mg l-1) as well as the effect of the xenobiotic on fungal amino acids ...
Adrian Soboń   +52 more
core   +1 more source

Enhanced mitochondrial respiration in peripheral blood mononuclear cells (PBMCs) from young children with overweight/obesity and insulin resistance

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
We investigated measures of mitochondrial function in certain types of blood cells and metabolism in 65 children, 5–10 years old. Compared to children of normal weight (n = 20), children with overweight/obesity (n = 28) and especially those with insulin resistance (n = 17), differed in how their cells produced energy.
Eugenia Carvalho   +5 more
wiley   +1 more source

Lack of complex I activity in human cells carrying a mutation in MtDNA-encoded ND4 subunit is corrected by the Saccharomyces cerevisiae NADH-quinone oxidoreductase (NDI1) gene [PDF]

open access: yes, 2001
The gene for the single subunit, rotenone-insensitive, and flavone-sensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae (NDI1) can completely restore the NADH dehydrogenase activity in mutant human cells that lack the essential ...
Attardi, Giuseppe   +7 more
core   +1 more source

Combating muscle atrophy: emerging therapeutic targets that are fiber‐type‐specific

open access: yesThe FEBS Journal, EarlyView.
Inflammation, denervation or decreased insulin signaling activate proteolysis and cause muscle wasting. Pathological conditions like obesity and DMD can also exacerbate atrophy via PGD2–RhoA–ROCK2 signaling. In contrast, exercise, dietary interventions, and pharmacological agents can activate Ca2+/calcineurin–NFAT and AMPK–PGC‐1α–MEF pathways ...
Samrat Chakraborty   +2 more
wiley   +1 more source

RESPONS IMUN DAN PEMERIKSAAN SEROLOGI PADA TUBERKULOSIS

open access: yesSaintika Medika, 2012
Tuberculosis merupakan penyakit yang biasanya menyerang paru-paru. Inhalasi droplet yang mengandung sedikit bakteri Mycobacterium tuberculosis ditelan oleh makrofag alveolar.
Diah Hermayanti
doaj   +1 more source

Complete genome sequence of Syntrophobacter fumaroxidans strain (MPOB(T)). [PDF]

open access: yes, 2012
Syntrophobacter fumaroxidans strain MPOB(T) is the best-studied species of the genus Syntrophobacter. The species is of interest because of its anaerobic syntrophic lifestyle, its involvement in the conversion of propionate to acetate, H2 and CO2 during ...
Crable, Bryan R   +15 more
core   +2 more sources

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

open access: yesThe FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza   +4 more
wiley   +1 more source

A short peptide derived from late embryogenesis abundant proteins enhances acid tolerance in Escherichia coli via modulation of two‐component regulatory systems

open access: yesThe FEBS Journal, EarlyView.
Expression of the LEA‐K peptide in E. coli BL21 (DE3) improved bacterial viability under acidic stress (pH4), suggesting a protective function. RNA‐sequencing of LEA‐K‐expressing vs. non‐expressing cells revealed 283 differentially expressed genes (DEGs). In silico docking linked LEA‐K to two‐component systems (TCS) proteins (Rcs, BtsS/R, and EnvZ/OmpR)
Khaled Metwally, Shinya Ikeno
wiley   +1 more source

Blue light‐induced stomatal opening is associated with species‐specific changes in primary metabolism but not with starch breakdown in guard cells

open access: yesNew Phytologist, EarlyView.
Summary Blue light (BL)‐induced stomatal opening has been associated with starch breakdown within Arabidopsis guard cells (GCs). However, whether this mechanism is conserved in angiosperms and which metabolic pathways are activated downstream of BL perception and/or starch degradation, remains unknown.
Humaira Bahadar   +7 more
wiley   +1 more source

A purple non-sulfur bacterium producing polyhydroxybutyrate and the conserved region of pha synthase gene

open access: yesBioscience Journal, 2016
This study aimed to screen purple non-sulfur bacteria capable of accumulating granules or polyhydroxybutyrate (PHB) inside the cells, identify the potent strain, assay the enzyme or PHA synthase, and compare the PHB synthase gene with that of related ...
Somporn Tanskul   +2 more
doaj   +3 more sources

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