Results 281 to 290 of about 324,763 (345)

Endosymbiosis in trypanosomatids: the bacterium regulates the intermediate and oxidative metabolism of the host cell. [PDF]

open access: yesmSphere
Barrinha A   +7 more
europepmc   +1 more source

Malate synthase in insects

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1974
Abstract 1. 1. Malate synthase has been identified in insects. 2. 2. Malate formation depended on the presence of both glyoxylate and acetyl-CoA and was linear with time. 3. 3. In the mosquito, activity was very weak at emergence, but developed within 6–8 days in unfed, blood-fed and sugar-fed groups. 4. 4.
G E, Skye, E, Van Handel
openaire   +2 more sources

Structural and energetic understanding of novel natural inhibitors of Mycobacterium tuberculosis malate synthase

Journal of Cellular Biochemistry, 2018
Persistent infection by Mycobacterium tuberculosis requires the glyoxylate shunt. This is a bypass to the tricarboxylic acid cycle in which isocitrate lyase (ICL) and malate synthase (MS) catalyze the net incorporation of carbon during mycobacterial ...
R. Shukla, Harish Shukla, Timir Tripathi
semanticscholar   +1 more source

The malate synthase gene of cucumber

Plant Molecular Biology, 1989
The complete sequences of a full-length cDNA clone and a genomic clone encoding the Cucumis sativus glyoxysomal enzyme malate synthase, have been determined. The sequences have enabled us to identify putative control regions at the 5' end of the gene, three introns, and possible alternative polyadenylation sites at the 3' end.
I A, Graham   +4 more
openaire   +2 more sources

Anion-π Interactions in Computer-Aided Drug Design: Modeling the Inhibition of Malate Synthase by Phenyl-Diketo Acids

Journal of Chemical Information and Modeling, 2018
Human infection by Mycobacterium tuberculosis (Mtb) continues to be a global epidemic. Computer-aided drug design (CADD) methods are used to accelerate traditional drug discovery efforts.
Jill F Ellenbarger   +7 more
semanticscholar   +1 more source

Malate synthase from Gossypium hirsutum

Phytochemistry, 1981
Abstract Malate synthase was purified 2000-fold from cotyledons of dark-germinated cotton, Gossypium hirsutum . The purified enzyme had a pH optimum of 8.2, and an absolute requirement for a divalent cation. Only glyoxylate and acetyl-CoA served as condensation partners. Results obtained with functional-group directed inhibitors suggest the presence
Jan A. Miernyk, Richard N. Trelease
openaire   +1 more source

Oligomerization of malate synthase during glyoxysome biosynthesis

Archives of Biochemistry and Biophysics, 1983
The octameric malate synthase, found in glyoxysomes of plants, is synthesized as monomeric precursor in the cytoplasm. The precursor form does not possess a different subunit molecular weight than the mature organellar enzyme, but differs from the organellar protein by not oligomerizing and aggregating.
C, Kruse, H, Kindl
openaire   +2 more sources

Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 2-F-3-Methyl-6-F-phenyldiketoacid

, 2018
Human infection by Mycobacterium tuberculosis (Mtb) continues to be a global epidemic. Computer-aided drug design (CADD) methods are used to accelerate traditional drug discovery efforts.
Jill F Ellenbarger   +7 more
semanticscholar   +1 more source

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