Results 101 to 110 of about 7,790 (296)

Deficiency of 2‐Oxoglutarate Carrier (Slc25a11) Drives RPE Epithelial‐to‐Mesenchymal Transition and Exacerbates Subretinal Fibrosis in Neovascular Age‐Related Macular Degeneration

Aging Cell, EarlyView.
The diagram shows that OGC deficiency leads to mitochondrial dysfunction, which activates the PI3K/AKT/Slug pathway and triggers epithelial‐mesenchymal transition (EMT) in retinal pigment epithelial cells. This process promotes myofibroblast accumulation and subretinal fibrosis in laser‐induced CNV, contributing to the progression of AMD.
Mo Wang, Feng‐Juan Gao, Wenyi Tang, Boya Lei, Fangyuan Hu, Jun Ma, Srinivas R. Sadda, Ram Kannan, Parameswaran G. Sreekumar, Gezhi Xu   +9 more
wiley   +1 more source

The preparation of the optical isomers of miotine [PDF]

, 1932
The present investigation was undertaken with the object of developing a method for the preparation of the stereoisomerides of the methyl urethane of a- m- hydroxyphenylethyldimethylamine ( formula I) in amounts which would render them available for
Macdonald, Joseph McLean
core  

Revealing the Diverse Allergenic Protein Repertoire of Six Widely Consumed Crab Species: A Species‐Specific Allergen in King Crab

Allergy, EarlyView.
This study comprehended the allergen profiles of six edible crab species using proteomic and transcriptomic analyses and identified 11 putative allergens. King crab has a distinct protein and allergen profile, with the discovery of malate dehydrogenase as a novel king crab‐specific allergen registered as Para c 11.
Shanshan Li, Jingyuan Bian, Qing Xiong, Brian Shing‐Hei Wong, Stephen Kwok‐Wing Tsui, Kin‐Ming Kwan, Nicki Yat‐Hin Leung, Ting‐Fan Leung, Patrick S. C. Leung, Ka‐Hou Chu, Xiaojun Xiao, Christine Yee‐Yan Wai   +11 more
wiley   +1 more source

Purification and Chemical Characterization of Malate Dehydrogenase of Bacillus subtilis

, 1965
Akira Yoshida
openalex   +1 more source

Cofactor requirements of the l-malate dehydrogenase of Pseudomonas ovalis Chester [PDF]

, 1966
PJ Phizackerley, MJ Francis
openalex   +1 more source

Protective Role for Itaconate During Inhaled Allergen Challenge

Allergy, EarlyView.
Itaconate levels decrease in sputum following allergen inhalation in mild asthmatics, suggesting a dynamic metabolic response to airway challenge. Genetic deletion of Acod1 in mice did not alter airway inflammation or remodelling in response to chronic HDM exposure.
Gesa J. Albers, Patricia P. Ogger, Christina Michalaki, Helen Stölting, Simone A. Walker, Anna Caldwell, John M. Halket, Kathryn Duvall, Atia Batool, Lisha Joshi, Helen O'Brien, Cormac McCarthy, Timothy Hinks, Gail M. Gauvreau, Paul M. O'Byrne, Clare M. Lloyd, Adam J. Byrne   +16 more
wiley   +1 more source

Studies on the Presence and Role of Tryptophan in Pig Heart Mitochondrial Malate Dehydrogenase

, 1968
Tsun‐Leung Chan, Karl A. Schellenberg
openalex   +1 more source

Aspects of malate metabolism by slices and mitochondria from carrot tissue [PDF]

, 1962
L. Dalgarno, L.M. Birt
openalex   +1 more source

Composition of Arkansas Grapes During Maturation [PDF]

, 1976
Changes in organic acid and glucose content during maturation and ripening of grapes grown in Arkansas in 1973 are shown for four French hybrid varieties, S5279, S10878, SV23- 657, and S13053, and for four rotundifolia varieties, Scuppernong, Tarheel ...
Jones, Cameron, Whitley, Thomas O., Yang, Dominic T.C.   +2 more
core   +1 more source

Biallelic TMEM126B Variants as a Novel Cause of Kidney Failure—Implications for Mitochondrial Genetic Testing in Nephrology

Clinical Genetics, EarlyView.
An adult with kidney failure had compound‐heterozygous TMEM126B variants causing mitochondrial complex I deficiency. This expands TMEM126B to mitochondrial nephropathy and supports including mitochondrial genes in renal genetic testing.
Zachary T. Sentell, Anthony C. T. Cheung, Felicia Russo, Chantal Bernard, Rita Suri, Andrey V. Cybulsky, Daniela Buhas, Thomas M. Kitzler   +7 more
wiley   +1 more source