Results 161 to 170 of about 1,409 (224)

Evolutionary history and recombination in the mitochondrial carrier SLC25 superfamily analyzed by similarities in the exon and transmembrane α‐helix sequences

open access: yesProtein Science, Volume 35, Issue 8, August 2026.
Abstract Mitochondrial carriers (MCs), which constitute a superfamily also called the solute carrier family 25 (SLC25), are characterized by conserved signature motif sequences and a six‐transmembrane α‐helical transporter domain. They transport a wide variety of substrates ranging from protons, inorganic ions, citric acid cycle intermediates, and ...
Magnus Monné   +5 more
wiley   +1 more source

DNA‐Enzyme Hybrid Nanostructures: Functional Materials to Modulate Enzymatic Activity

open access: yesSmall, Volume 22, Issue 43, 3 August 2026.
DNA–enzyme hybrid nanostructures enable precise spatial and stoichiometric control over enzyme organization, offering a powerful platform to modulate catalytic activity. This review critically evaluates key mechanistic hypotheses, including proximity effects, microenvironment changes, confinement, and stabilization, as well as highlighting ...
Manar Elnaggar, Amelie Heuer‐Jungemann
wiley   +1 more source

A pathway toward clinical translation of hyperpolarized [1,4-<sup>13</sup>C<sub>2</sub>,2,3-d<sub>2</sub>]fumarate as an imaging biomarker for early cellular necrosis in vivo. [PDF]

open access: yesMagn Reson Med
Birchall JR   +25 more
europepmc   +1 more source
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Sunitinib malate

Cancer Chemotherapy and Pharmacology, 2006
Recently, there has been a growing interest in understanding the role of receptor tyrosine kinases (RTK), such as vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR), stem cell factor receptor (KIT), and fms-like tyrosine kinase 3 (FLT3), in promoting tumor angiogenesis, tumor growth and metastasis ...
Hassane, Izzedine   +3 more
openaire   +2 more sources

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