Results 171 to 180 of about 1,480 (260)

Branched‐Chain Amino and Keto Acids Reduce Hepatocyte Lipid Droplet Size and Number via Distinct Proteomic Pathways

PROTEOMICS, Volume 26, Issue 7, Page 146-157, July 2026.
ABSTRACT Branched‐chain amino acids (BCAA) and their corresponding keto acids (BCKA) have been associated with changes in hepatic lipid metabolism and the resulting alterations in intracellular triglyceride concentrations. In this study, we utilized a previously established hepatocyte model to investigate the impact of BCAA and BCKA supplementation on ...
Jayasimha R. Daddam, Mounica Sura, Edward Kolodziej, Maria Gojcaj, Zheng Zhou   +4 more
wiley   +1 more source

Sex dimorphism and substrate dependency of liver mitochondrial bioenergetics and H₂O₂ production. [PDF]

Am J Physiol Gastrointest Liver Physiol
Dave DD, Taheri P, Boovarahan SR, Kim J, Cowley AW, Audi SH, Dash RK.   +6 more
europepmc   +1 more source

Structure–activity relationship study shows versatility in substrate specificity for heterodisulfide reductase in methanogenic archaea

Protein Science, Volume 35, Issue 7, July 2026.
Abstract Hydrogenotrophic methanogens are anaerobic archaea that convert carbon dioxide and hydrogen into methane. Central to this process is the heterodisulfide reductase (Hdr), which catalyzes the reduction of the heterodisulfide made of coenzyme M and coenzyme B. In vivo, Hdr functions in association with electron‐donating modules such as the [NiFe]‐
Mahdi Faal Maleki, Joakim Bøgelund Jakobsen, Eva Danielle Schuiten, Tristan Wagner, André Luis Alves Neves, Lennart Bunch   +5 more
wiley   +1 more source

RIPK3 promotes ASIC1a-mediated fibroblast-like synoviocyte migration and invasion via malate shuttle-driven mitochondrial respiration in rheumatoid arthritis. [PDF]

Theranostics
Hu W, Wang K, Dong Y, Xu Y, Xing J, Zhu J, Ding J, Zhao Y, Xu Y, Cheng Y, Peng X, Zhou R, Hu W, Chen F.   +13 more
europepmc   +1 more source

Study of copper(II) malates complexed with imidazole or methyl substituted imidazoles

, 1992
J.F. Le Querler, A. Busnot, J.F. Hemidy, J. Masson   +3 more
core   +1 more source

Molecular architecture of the human citrate synthase–malate dehydrogenase 2 metabolon

Acta Crystallographica Section D, Volume 82, Issue 7, Page 740-750, July 2026.
Human malate dehydrogenase forms a transient complex with citrate synthase.Metabolons are transient biomolecular complexes that enhance the efficiency of metabolic pathways through substrate channeling. These complexes are difficult to study because of their transient nature, thus limiting our understanding of how they are formed and regulated.
Angela J. Kayll, Umanga Rupakheti, Renee St John, Gabriel Rementeria, Joseph J. Provost, Christopher E. Berndsen   +5 more
wiley   +1 more source

Malate targets pyruvate kinase M2 to promote colorectal cancer cell cycle arrest and tumor suppression. [PDF]

Mol Biomed
Zhao K, Zhang F, Qin Q, Zhang D, Yang F, Huang Y, Deng R, Jing H, Xiao W, Miao H, Shi R.   +10 more
europepmc   +1 more source

Iron, nickel and zinc malates coordination compounds cynthesis, characterization and thermal behaviour

, 2004
I. Mindru, E. Segal, L. Patron, O. Carp, G. Marinescu   +4 more
core   +1 more source

Putative involvement of lncRNA, miRNA, and mRNA‐mediated ceRNA network regulation in drought priming to enhance drought tolerance in Nicotiana tabacum

Annals of Applied Biology, Volume 189, Issue 1, July 2026.
Drought priming increased the tolerance of Nicotiana tabacum to severe, recurring drought stress by modulating the expression of stress‐related genes via long non‐coding RNAs (lncRNAs), which acted as competing endogenous RNAs (ceRNAs) for microRNAs (miRNAs) and messenger RNAs (mRNAs).
Fatma Aydinoglu, Elif Yalvac
wiley   +1 more source

Enabling malic acid production from corn-stover hydrolysate in Lipomyces starkeyi via metabolic engineering and bioprocess optimization. [PDF]

Microb Cell Fact
Czajka JJ, Dai Z, Radivojević T, Kim J, Deng S, Lemmon T, Swita M, Burnet MC, Munoz N, Gao Y, Kim YM, Hofstad B, Magnuson JK, Garcia Martin H, Burnum-Johnson KE, Pomraning KR.   +15 more
europepmc   +1 more source