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Cancer Chemotherapy and Pharmacology, 2006
Recently, there has been a growing interest in understanding the role of receptor tyrosine kinases (RTK), such as vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR), stem cell factor receptor (KIT), and fms-like tyrosine kinase 3 (FLT3), in promoting tumor angiogenesis, tumor growth and metastasis ...
Irina Buhaescu +3 more
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Recently, there has been a growing interest in understanding the role of receptor tyrosine kinases (RTK), such as vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR), stem cell factor receptor (KIT), and fms-like tyrosine kinase 3 (FLT3), in promoting tumor angiogenesis, tumor growth and metastasis ...
Irina Buhaescu +3 more
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Sources of intramitochondrial malate
The FASEB Journal, 1989Liver mitochondria from rats treated with gluconeogenic hormones or subjected to vigorous exercise consume oxygen more rapidly than do mitochondria from control rats. These treatments result in elevated mitochondrial malate concentrations, which facilitate the entry of added substrate into the mitochondria.
Bobyleva Guarriero V +3 more
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Utilization of malate or aspartate by a yeast lacking malate enzyme
Archiv f�r Mikrobiologie, 1968Hansenula anomala, a yeast lacking malate enzyme, was able to grow in media containing malate or aspartate as sole carbon and energy sources. Both aspartate-α-ketoglutarate transaminase and pyruvate kinase activities changed their levels when the yeast was grown on different carbon sources.
Manuel Losada +3 more
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Malate dismutation by Desulfovibrio
Archiv f�r Mikrobiologie, 19701. Nine strains of Desulfovibrio, representing 4 species, grew by dismutation of malate in “sulphate-free” medium; succinate, fumarate and acetate were end-products of growth. 2. Two strains of D. vulgaris could only grow in malate medium in presence of sulphate as terminal electron acceptor. 3.
J. D. A. Miller +3 more
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Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1974
Abstract 1. 1. Malate synthase has been identified in insects. 2. 2. Malate formation depended on the presence of both glyoxylate and acetyl-CoA and was linear with time. 3. 3. In the mosquito, activity was very weak at emergence, but developed within 6–8 days in unfed, blood-fed and sugar-fed groups. 4. 4.
Emile van Handel, George E. Skye
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Abstract 1. 1. Malate synthase has been identified in insects. 2. 2. Malate formation depended on the presence of both glyoxylate and acetyl-CoA and was linear with time. 3. 3. In the mosquito, activity was very weak at emergence, but developed within 6–8 days in unfed, blood-fed and sugar-fed groups. 4. 4.
Emile van Handel, George E. Skye
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2012
Sunitinib malate (Sutent®, Pfizer Inc.) is a multitargeted tyrosine kinase inhibitor that inhibits tumor cell proliferation and angiogenesis. It is approved for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).
Mohammed Gabr Kassem +2 more
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Sunitinib malate (Sutent®, Pfizer Inc.) is a multitargeted tyrosine kinase inhibitor that inhibits tumor cell proliferation and angiogenesis. It is approved for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).
Mohammed Gabr Kassem +2 more
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The Identity of “Chromium Malate”
Biological Trace Element Research, 2017Recently, several studies on the effects of a compound named "chromium malate," with the proposed formula "Cr2malate3·xH2O" where x = 3.5 or 5, on the health of healthy and diabetic rats have appeared. However, the compound is poorly characterized, and knowing the identity of this material could be important in the interpretation of the previous and of
Michael K. Bowman +5 more
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Flow-injection determination of malate with immobilized malate dehydrogenase
Analytica Chimica Acta, 1989Abstract Malate dehydrogenase (MDH) is immobilized chemically on controlled-pore glass and used on-line in a glass minicolumn (25×2.5 mm i.d.). Malate solution passes through the minicolumn of immobilized MDH and the NADH formed is monitored spectrophotometrically from 9 × 10-−4 down to 7 × 10−6 M (36 ng in 40 μl) at 50 samples h−1.
Ala'ddin M. Almuiabed, Alan Townshend
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A Bienzyme Electrode Probe for Malate
Analytical Chemistry, 1996A new amperometric malate enzyme electrode probe has been constructed using a hydrogen peroxide-based sensor coupled with malic and pyruvate oxidase enzymes. The first enzyme catalyzes the oxidation of malic acid, which in the presence of NADP+ yields pyruvate as product.
MESSIA, Maria Cristina +3 more
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