Results 71 to 80 of about 7,875 (302)

Structure ofN,N-dimethylaminopyridiniumL-malate [PDF]

open access: bronze, 2005
A. Criado   +7 more
openalex   +1 more source

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

open access: yesInterdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui   +12 more
wiley   +1 more source

Extraction and study of enzymes linked to malate metabolism in tree leaves [PDF]

open access: bronze, 1989
Dominique Gérant   +3 more
openalex   +1 more source

Wild‐Derived House Mice (Mus musculus) Are Able to Cope With a Constant Light Environment

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Exposure to altered nighttime lighting conditions has become common in today's modern world. Light at night disrupts circadian processes that govern feeding patterns, sleep/wake cycles, and metabolic homoeostasis, increasing the risk of developing pathologies associated with cardiometabolic disease. Yet, the underlying mechanism(s) responsible
Kevin Pham   +4 more
wiley   +1 more source

Biomarkers for the estimation of isoproterenol‐induced myocardial infarction: A review of key parameters

open access: yesJournal of Intelligent Medicine, EarlyView.
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran   +5 more
wiley   +1 more source

Hypoxia‐Induced Histone Lactylation Promotes Ferroptosis in Cardiomyocytes via the Wnt/β‐Catenin Pathway

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study investigated the effects of histone lactylation on ferroptosis in hypoxia‐induced cardiomyocytes. A hypoxia model was established in AC16 cells treated with 2‐Deoxy‐D‐glucose (2‐DG, a glucose analogue), ferrostatin‐1 (Fer‐1, a selective ferroptosis inhibitor), lactate (LA), sh‐β‐catenin (shRNA of β‐catenin), or SKL2001 (an agonist ...
Xin‐Hua Zhu   +6 more
wiley   +1 more source

Non‐Histone Lactylation: A New Frontier in Cerebral Ischemia‐Reperfusion Injury

open access: yesMed Research, EarlyView.
ABSTRACT Reperfusion therapy is the mainstay of treatment for ischemic stroke (IS) but frequently exacerbates secondary injury. Following cerebral ischemia and hypoxia, lactate accumulates markedly. Traditionally regarded as a metabolic byproduct, lactate has gained new significance with the discovery of protein lactylation. In addition to experimental
Minghui Tang   +13 more
wiley   +1 more source

A Self‐Healing Conductive PVP/SUM Hydrogel for Real‐Time Human Motion Detection

open access: yesNano Select, EarlyView.
The PVP/SUM hydrogel exhibits self‐healing, conductivity, and strong mechanical performance due to H‐bonds and dipole–dipole interactions. It elongates up to 330% and shows fracture strength between 0.9 and 1.5 MPa under varying strain rates. With a conductivity of 3.28 × 10−5 S/cm, it responds rapidly to human motion, enabling real‐time monitoring for
Vinnakoti Meghana, Illa Ramakanth
wiley   +1 more source

In vitro investigations of Cumin oil as antioxidants agent on fresh and fried edible oil Faroug Bakheit [PDF]

open access: yes, 2018
oai:ojs2.jmcrr.in:article/5This study was designed to determine the effect of cumin oil as antioxidant on the chemical properties ofstored sunflower oil.
Ahmed, Mohamed
core   +1 more source

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