Results 71 to 80 of about 7,790 (296)

C9orf72 Repeat Expansion Induces Metabolic Dysfunction in Human iPSC‐Derived Microglia and Modulates Glial‐Neuronal Crosstalk

open access: yesGlia, EarlyView.
C9orf72 microglia display heightened glycolysis and oxidative stress, driving astrocytic reprogramming that impacts motor neurons. iPSC tricultures uncover key glial–neuronal interactions in C9orf72 pathology. ABSTRACT The C9orf72 hexanucleotide repeat expansion mutation is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and ...
Marika Mearelli   +12 more
wiley   +1 more source

Malate metabolism in mycobacteria [PDF]

open access: yesBiochemical Journal, 1972
Venkitasubramanian Ta   +2 more
openaire   +3 more sources

Oxidative phosphorylation at the crossroads of cancer: Metabolic orchestration, stromal collusion, and emerging therapeutic horizons

open access: yesInterdisciplinary Medicine, EarlyView.
Although most cancer cells rely on aerobic glycolysis, Oxidative phosphorylation (OXPHOS) remains essential for their survival, proliferation, and metastasis. With the emergence of OXPHOS‐targeted drugs, its therapeutic potential is becoming increasingly evident.
Keke Chen   +5 more
wiley   +1 more source

Technologies and Strategies for Metabolic and Molecular Imaging With Hyperpolarized MRI

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Conventional Magnetic Resonance Imaging (MRI) offers limited sensitivity for direct metabolic and molecular imaging using non‐proton nuclei due to low thermal nuclear spin polarization. Hyperpolarization (HP) technologies increase nuclear spin polarization by several orders of magnitude, overcoming this limitation to enable in vivo studies of ...
Alixander S. Khan, Christoffer Laustsen
wiley   +1 more source

Isoenzymes of Malate Dehydrogenase in Saccharomyces cerevisiae [PDF]

open access: bronze, 1968
W. Atzpodien   +3 more
openalex   +1 more source

Iron physiology and metabolism of model phytoplankton taxa in a western boundary continental shelf ecosystem

open access: yesLimnology and Oceanography, EarlyView.
Abstract Continental shelf ecosystems support diverse phytoplankton communities that contribute to global primary productivity. Iron is an important micronutrient controlling the growth of marine phytoplankton, but its role in influencing phytoplankton ecophysiology in western boundary continental shelf ecosystems is understudied.
Lucy E. Quirk   +2 more
wiley   +1 more source

In vitro investigations of Cumin oil as antioxidants agent on fresh and fried edible oil Faroug Bakheit [PDF]

open access: yes, 2018
oai:ojs2.jmcrr.in:article/5This study was designed to determine the effect of cumin oil as antioxidant on the chemical properties ofstored sunflower oil.
Ahmed, Mohamed
core   +1 more source

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