Results 1 to 10 of about 65,997 (164)

Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS) Analysis for the Identification of Pathogenic Microorganisms: A Review

open access: yesMicroorganisms, 2021
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been used in the field of clinical microbiology since 2010.
Xiao Meng, Ying-Chun Xu, Po-Ren Hsueh
exaly   +3 more sources

Current Scenario and Challenges in the Direct Identification of Microorganisms Using MALDI TOF MS

open access: yesMicroorganisms, 2021
MALDI TOF MS-based microbial identification significantly lowers the operational costs because of minimal requirements of substrates and reagents for extraction.
Young-Su Jeong
exaly   +3 more sources

How MALDI-TOF Mass Spectrometry Technology Contributes to Microbial Infection Control in Healthcare Settings

open access: yesVaccines, 2022
Healthcare settings have been utilizing matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) since 2010. MALDI-TOF MS has various benefits over the conventional method of biochemical identification, including ease ...
Ayman Elbehiry   +2 more
exaly   +3 more sources

Performance and additional benefits of MALDI-TOF-MS in M-protein detection in plasma cell disorders [PDF]

open access: yesAnnals of Medicine
Purposes Current methods for detecting monoclonal (M) proteins, such as immunofixation electrophoresis (IFE), serum protein electrophoresis (SPEP) and serum free light chains (sFLC), are limited by insufficient sensitivity and suboptimal efficiency. This
Mengmeng Dong   +11 more
doaj   +2 more sources

Making MALDI-TOF MS for entomological parameters accessible: A practical guide for in-house library creation. [PDF]

open access: yesPLoS ONE
Matrix-assisted laser desorption-ionisation time of flight mass spectrometry (MALDI-TOF MS) is a powerful analytical method that has been used extensively to identify sample ions of complex mixtures, and biological samples such as proteins, tissues and ...
Jonathan Karisa   +11 more
doaj   +2 more sources

Performance of MALDI–TOF Mass Spectrometry in the Philippines

open access: yesTropical Medicine and Infectious Disease, 2021
Identification of the causative pathogen in infectious diseases is important for surveillance and to guide treatment. In low- and middle-income countries (LMIC), conventional culture and identification methods, including biochemical methods, are ...
Morichika Osa   +16 more
doaj   +1 more source

Matrix-assisted laser desorption ionization-time of flight mass spectrometry for the identification of clinically relevant bacteria. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) allows rapid and reliable identification of microorganisms, particularly clinically important pathogens.
Cinzia Benagli   +4 more
doaj   +1 more source

A high-throughput MALDI-TOF MS biochemical screen for small molecule inhibitors of the antigen aminopeptidase ERAP1

open access: yesSLAS Discovery, 2023
MALDI-TOF MS is a powerful analytical technique that provides a fast and label-free readout for in vitro assays in the high-throughput screening (HTS) environment.
Leonie Müller   +11 more
doaj   +1 more source

Immuno-MALDI-TOF-MS in the Clinic [PDF]

open access: yesClinical Chemistry, 2018
There is an ever-increasing need for robust and cost-effective methods that allow researchers and clinicians to detect molecular signatures of disease from patient samples, such as biofluids or biopsies. Traditional methods for measuring protein concentrations often lack specificity, precision, throughput, or robustness.
René P, Zahedi   +2 more
openaire   +2 more sources

Performance evaluation and clinical validation of optimized nucleotide MALDI-TOF-MS for mycobacterial identification

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
ObjectiveTo evaluate the performance and validate the diagnostic value of a nucleotide matrix-assisted laser desorption time-of-flight mass spectrometry (MALDI-TOF-MS) with the analysis process optimized in identification of mycobacterium species ...
Baiying Li   +13 more
doaj   +1 more source

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