Results 1 to 10 of about 67,841 (262)

Current Status of Matrix-Assisted Laser Desorption/Ionization–Time-of-Flight Mass Spectrometry (MALDI-TOF MS) in Clinical Diagnostic Microbiology

Molecules, 2020
Mass spectrometry (MS), a core technology for proteomics and metabolomics, is currently being developed for clinical applications. The identification of microorganisms in clinical samples using matrix-assisted laser desorption/ionization–time-of-flight ...
Sachio Tsuchida, Hiroshi Umemura, Tomohiro Nakayama   +2 more
doaj   +1 more source

Performance of a Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Testing Algorithm for the Rapid Identification of Clinical Filamentous Molds

Frontiers in Cellular and Infection Microbiology, 2022
One of the most significant challenges in the treatment of fungal infections is the relatively long turnaround time (TAT) required for fungal species identification.
John A. Fissel, John A. Fissel, Carrie K. Holdren-Serrell, Warda Memon, Sean X. Zhang, Sean X. Zhang   +5 more
doaj   +1 more source

Identification of Mycobacterium abscessus using the peaks of ribosomal protein L29, L30 and hemophore-related protein by MALDI-MS proteotyping

Scientific Reports
Mycobacteroides (Mycobacterium) abscessus, which causes a variety of infectious diseases in humans, is becoming detected more frequently in clinical specimens as cases are spreading worldwide. Taxonomically, M.
Satomi Takei, Kanae Teramoto, Yuji Sekiguchi, Hiroaki Ihara, Mari Tohya, Shinichi Iwamoto, Koichi Tanaka, Abdullah Khasawneh, Yuki Horiuchi, Shigeki Misawa, Toshio Naito, Teruo Kirikae, Tatsuya Tada, Yoko Tabe   +13 more
doaj   +1 more source

MALDI-TOF MS Is an Effective Technique To Classify Specific Microbiota

Microbiology Spectrum, 2023
MALDI-TOF MS is well-recognized for single microbial identification and widely used in research and clinical fields due to its specificity, speed of analysis, and low cost of consumables.
Liangqiang Chen, Wenjing Gao, Xue Tan, Ying Han, Fu Jiao, Bin Feng, Jinghang Xie, Bin Li, Huilin Zhao, Huabin Tu, Shaoning Yu, Li Wang   +11 more
doaj   +1 more source

MALDI-TOF MS Analysis of Native and Permethylated or Benzimidazole-Derivatized Polysaccharides

Molecules, 2012
MALDI-TOF MS provides rapid and sensitive analyses of larger biomolecules. However, MS analyses of polysaccharide have been reported to have lower sensitivity compared to peptides and proteins.
Chung-Hsuan Chen, Wen-Bin Yang, Hui-Ming Yu, Yi-Ting Chen, Shwu-Huey Wang, Wei-Ting Hung   +5 more
doaj   +1 more source

MALDI-TOF Mass Spectrometry: A Powerful Tool for Clinical Microbiology at Hôpital Principal de Dakar, Senegal (West Africa). [PDF]

PLoS ONE, 2015
Our team in Europe has developed the routine clinical laboratory identification of microorganisms by matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry (MS). To evaluate the utility of MALDI-TOF MS in tropical Africa
Cheikh I Lo, Bécaye Fall, Bissoume Sambe-Ba, Silman Diawara, Mamadou W Gueye, Oleg Mediannikov, Cheikh Sokhna, Ngor Faye, Yaya Diemé, Boubacar Wade, Didier Raoult, Florence Fenollar   +11 more
doaj   +1 more source

MALDI-TOF MS for the Diagnosis of Infectious Diseases [PDF]

Clinical Chemistry, 2015
Abstract BACKGROUND First introduced into clinical microbiology laboratories in Europe, MALDI-TOF MS is being rapidly embraced by laboratories around the globe. Although it has multiple applications, its widespread adoption in clinical microbiology relates to its use as an inexpensive, easy, fast, and
openaire   +2 more sources

Identification of ticks from North of Italy by MALDI-TOF MS

Ticks and Tick-Borne Diseases
Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) has recently emerged as a promising method for arthropods identification. A total of 125 ticks collected from 2013 until 2023 in Italy either stored frozen at –20
Maria Sampieri, Adama Zan Diarra, Lionel Almeras, Annalisa Grisendi, Mara Scremin, Giulia Maioli, Philippe Parola   +6 more
doaj   +1 more source

MALDI-TOF MS in the Microbiology Laboratory: Current Trends [PDF]

Current Issues in Molecular Biology, 2017
Within less than a decade matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has become a gold standard for microbial identification in clinical microbiology laboratories. Besides identification of microorganisms the typing of single strains as well as the antibiotic and antimycotic resistance testing has come ...
Sören, Schubert, Markus, Kostrzewa
openaire   +2 more sources

Quantitative Approach to Single-Nucleotide Polymorphism Analysis Using MALDI-TOF Mass Spectrometry

BioTechniques, 2000
Pooling of DNA samples before genotyping is a valuable means of streamlining large-scale genotyping efforts in disease association studies, single-nucleotide polymorphism (SNP) validation or mutant allele screening programs.
Philip Ross, Laura Hall, Lawrence A. Haff   +2 more
doaj   +1 more source