Results 21 to 30 of about 213,931 (342)

Performance evaluation and clinical validation of optimized nucleotide MALDI-TOF-MS for mycobacterial identification

Frontiers in Cellular and Infection Microbiology, 2022
ObjectiveTo evaluate the performance and validate the diagnostic value of a nucleotide matrix-assisted laser desorption time-of-flight mass spectrometry (MALDI-TOF-MS) with the analysis process optimized in identification of mycobacterium species ...
Baiying Li, Chi Zhu, Lifang Sun, Hang Dong, Yaping Sun, Shangzhi Cao, Libo Zhen, Qi Qi, Quanquan Zhang, Ting Mo, Huijie Wang, Meihua Qiu, Chao Song, Qingshan Cai   +13 more
doaj   +1 more source

Immuno-MALDI-TOF-MS in the Clinic [PDF]

Clinical Chemistry, 2018
There is an ever-increasing need for robust and cost-effective methods that allow researchers and clinicians to detect molecular signatures of disease from patient samples, such as biofluids or biopsies. Traditional methods for measuring protein concentrations often lack specificity, precision, throughput, or robustness.
René P, Zahedi, Carol E, Parker, Christoph H, Borchers   +2 more
openaire   +2 more sources

MALDI-TOF MS in a Medical Mycology Laboratory: On Stage and Backstage

Microorganisms, 2021
The implementation of MALDI-TOF MS in medical microbiology laboratories has revolutionized practices and significantly reduced turnaround times of identification processes.
Marie G Robert, M. Cornet, Aurélie Hennebique, T. Rasamoelina, Yvan Caspar, L. Pondérand, M. Bidart, Harmonie Durand, M. Jacquet, C. Garnaud, D. Maubon   +10 more
semanticscholar   +1 more source

Direct Rapid Identification from Positive Blood Cultures by MALDI-TOF MS: Specific Focus on Turnaround Times

Microbiology spectrum, 2021
Using MALDI-TOF MS directly from blood culture bottles reduces the time required for pathogen identification, and the turnaround times for final identification have been compared with overnight incubation from solid media in previous studies.
Hazan Zengin Canalp, B. Bayraktar
semanticscholar   +1 more source

Rapid diagnosis of periprosthetic joint infection from synovial fluid in blood culture bottles by direct matrix-assisted laser desorption ionization time-of-flight mass spectrometry.

PLoS ONE, 2020
BackgroundThe aim of this prospective study was to use direct matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) to rapidly diagnose periprosthetic joint infections (PJIs).MethodSynovial fluid was taken from 77 ...
Feng-Chih Kuo, Chun-Chih Chien, Mel S Lee, Jun-Wen Wang, Po-Chun Lin, Chen-Hsiang Lee   +5 more
doaj   +1 more source

MALDI-TOF MS analysis of urinary nucleosides [PDF]

Journal of the American Society for Mass Spectrometry, 2005
As RNA turnover seems to be impaired in cancer patients, modified nucleosides have been evaluated as potential tumor markers. Modified nucleosides are mainly formed post-transcriptionally in tRNA, set free during RNA metabolism, and excreted in urine.
Kammerer, Bernd, Frickenschmidt, Antje, Gleiter, Christoph H., Laufer, Stefan, Liebich, Hartmut   +4 more
openaire   +2 more sources

Evaluation of three sample preparation methods for the identification of clinical strains by using two MALDI‐TOF MS systems

Journal of Mass Spectrometry, 2021
Matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry (MALDI‐TOF MS) has revolutionized the microbial identification, especially in the clinical microbiology laboratories. However, although numerous studies on the identification of
Jinghua Wang, Hualiang Wang, Keya Cai, Peijuan Yu, Yajuan Liu, Gaoling Zhao, Rong Chen, Rong Xu, Maowen Yu   +8 more
semanticscholar   +1 more source

Integrative Description of Cryptic Tigriopus Species From Korea Using MALDI-TOF MS and DNA Barcoding

Frontiers in Marine Science, 2021
MALDI Time-of-Flight Mass Spectrometry (MALDI-TOF MS) provides a fast and reliable alternative method for species-level identification of pathogens and various metazoans.
Jisu Yeom, Nayeon Park, Raehyuk Jeong, Wonchoel Lee   +3 more
doaj   +1 more source

MALDI-TOF MS ANALYSIS OF LONG-TERM STORED STOCK CANDIDA STRAINS IDENTIFIED BY MOLECULAR AND CONVENTIONAL METHODS

İstanbul Tıp Fakültesi Dergisi, 2021
Objective: In recent years, the rapid and accurate identification of Candida isolates at species level has been of great importance for reasons such as increased incidence of infections due to Candida species and differing antifungal susceptibilities by ...
Tuğrul Hoşbul, Fatih Şahiner, Ramazan Gümral, Sinem Kaya, Bayhan Bektöre, Kemal Tekin, Şinasi Taner Yıldıran   +6 more
doaj   +1 more source

Liquid MALDI MS analysis of complex peptide and proteome samples [PDF]

, 2016
Matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometry (MS) is well-known to be a powerful technique for the analysis of biological samples.
Hoffmann D. E., Kanjana Wiangnon, Rainer Cramer, Towers M., Yang Y., Zhu X.   +5 more
core   +1 more source