Results 151 to 160 of about 1,727,460 (299)
Journal of Infection in Developing CountriesIntroduction: To assess the diagnostic efficacy of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) for rapid and precise identification of Mycoplasma pneumoniae in clinical microbiology workflows ...
Ke Cen, Cong Qin, Jie Wang, Shenghai Wu
doaj +1 more source
, 2014 Differentially expressed proteins at different stages of lactation were identified by MALDI-TOF/TOF or LC-MS/MS.
Jagadeesh Janjanam (612978) +11 more
core +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
MALDI-TOF MS spectra of the discriminatory peaks.
, 2014 (A) MALDI-TOF MS spectrum of peak1 (861Da) in the disease group. (B) MALDI-TOF MS spectrum of peak1 (861Da) in the control group.
Ning Geng (325855) +6 more
core +1 more source
Recent Advances in Top‐Down Proteomics for Single‐Cell Research
Mass Spectrometry Reviews, EarlyView.ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley +1 more source
Development of a mass spectrometry diagnostic assay to monitor hepcidin levels in hemochromatosis patients [PDF]
, 2010 Hepcidin has been identified as the principle regulatory peptide essential for iron homeostasis. Expression of this cysteine-rich peptide is up-regulated by inflammation and iron overload, whereas hypoxia, iron deficiency and erythropoiesis suppress ...
Gay, Choon Lin Melvin
core
Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles
Mass Spectrometry Reviews, EarlyView.ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág +5 more
wiley +1 more source
Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics
Mass Spectrometry Reviews, EarlyView.ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers +5 more
wiley +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT Identification of a chemical agent yields insights into its physicochemical properties. By examining the intrinsic characteristics and environment of a compound, information about its history can be gathered. The main objective of authentication/forensic approaches to chemicals is to trace the history of the compound's origin, regardless of ...
Carla Orlandi +6 more
wiley +1 more source
Mass Spectrometry Imaging–Guided Proteomics, an Emerging Frontier in Spatial Biology
Mass Spectrometry Reviews, EarlyView.ABSTRACT Spatial heterogeneity is a defining feature of tissue organization, yet conventional proteomic analysis provides limited information about the spatial origins of identified proteins. Spatially guided proteomics addresses this limitation by using tissue imaging techniques to select regions of interest (ROIs) for localized analysis by liquid ...
Kenneth Weke +4 more
wiley +1 more source