Results 171 to 180 of about 213,931 (342)
Journal of Infection in Developing CountriesIntroduction: To assess the diagnostic efficacy of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) for rapid and precise identification of Mycoplasma pneumoniae in clinical microbiology workflows ...
Ke Cen, Cong Qin, Jie Wang, Shenghai Wu
doaj +1 more source
Ion Activation Methods for Top‐Down Proteomics
Mass Spectrometry Reviews, EarlyView.ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley +1 more source
First 20 Years of Orbitrap Mass Spectrometry as the Mainstream Analytical Technique
Mass Spectrometry Reviews, EarlyView.ABSTRACT This review traces the first 20 years of Orbitrap mass spectrometry as a mainstream high‑resolution and accurate‑mass (HR/AM) technology. It outlines the historical development of the Orbitrap analyzer, the evolution of major instrument families, and the key technological innovations that enabled its widespread adoption. Particular emphasis is
Alexander Makarov
wiley +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu +5 more
wiley +1 more source
Analyzing peptides and proteins by mass spectrometry: principles and applications in proteomics [PDF]
, 2012 Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166The study of proteins has been a key element in biomedicine and biotechnology because of their important role in cell functions or enzymatic activity. Cells are the basic unit of living
Estanyol i Ullate, Josep Maria +3 more
core +1 more source
Recent Advances in Top‐Down Proteomics for Single‐Cell Research
Mass Spectrometry Reviews, EarlyView.ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley +1 more source
Medicinal Research Reviews, EarlyView.ABSTRACT Boron neutron capture therapy (BNCT) is a targeted radiotherapy that exploits the selective accumulation of the 10B isotope within tumors, followed by irradiation with low‐energy neutrons to induce high linear energy transfer particles with short path lengths, resulting in localized tumor cell destruction while sparing surrounding healthy ...
Christoph Selg +2 more
wiley +1 more source
Результаты сравнительных исследований варианта внутреннего стандарта MALDI/TOF/MS с другими методами количественного анализа резвератрола [PDF]
, 2012 Рассмотрен вариант внутреннего стандарта MALDI/TOF/MS в сравнении с другими методами количественного анализа на примере субстанции ...
Васильев, Г. В. +2 more
core +1 more source
Modeling n‐Butyl Acrylate Polymerization using Complementary Modeling Techniques
Macromolecular Reaction Engineering, EarlyView.Two different simulation methods are used for the radical polymerization of nBA: deterministic in Predici and stochastic with mcPolymer. It has been successfully implemented across a wide temperature range. It turns out that the partially different implementation of chain‐length‐dependent termination and β‐scission are important for obtaining ...
Marco Drache +3 more
wiley +1 more source
Polyvinylidene Fluoride: Reaction Engineering and Applications
Macromolecular Reaction Engineering, EarlyView.An updated review on polyvinylidene fluoride (PVDF) is presented in this work. Its properties, important areas of application and different methods of production are described, with particular focus on emulsion polymerization, covering the latest advances in formulations and modeling studies.
Burak Hanamirian +2 more
wiley +1 more source