Results 121 to 130 of about 12,519,177 (391)

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

open access: yesMolecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban   +12 more
wiley   +1 more source

Investigating Learning Challenges Presented by Digital Technologies to Universities in the 21st Century: A Case Study [PDF]

open access: yes, 2014
There is now widespread recognition that digital technologies, particularly portable hand held devices capable of Internet connection, present opportunities and challenges to the way in which student learning is organized in schools, colleges and ...
Aldhafeeri, F, Male, T
core  

Learning-centred leadership or pedagogical leadership? An alternative approach to leadership in education contexts [PDF]

open access: yes, 2012
This paper critically reviews models of learning-centred leadership for self-determining educational organisations (i.e. those with a large degree of control over their own destiny and in vogue during the closing decades of the previous century) and ...
Male, Trevor, Palaiologou, Ioanna
core   +3 more sources

Perfluorooctanesulfonate (PFOS)-induced Sertoli cell injury through a disruption of F-actin and microtubule organization is mediated by Akt1/2

open access: yesScientific Reports, 2017
PFOS (perfluorooctanesulfonate, or perfluorooctane sulfonic acid) is an anthropogenic fluorosurfactant widely used in consumer products. While its use in Europe, Canada and the U.S.
Ying Gao   +6 more
doaj   +1 more source

Antioxidants for male subfertility.

open access: yesCochrane Database of Systematic Reviews, 2014
BACKGROUND Between 30% to 80% of male subfertility cases are considered to be due to the damaging effects of oxidative stress on sperm and 1 man in 20 will be affected by subfertility.
M. Showell   +5 more
semanticscholar   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

open access: yesMolecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun   +5 more
wiley   +1 more source

The Interactional Styles Used by Male and Female Chairpersons in Petra Christian University Student Executive Board Meetings [PDF]

open access: yes, 2014
This study examines the interactional styles related to the role of chairperson used by two female and two male chairpersons in the SEB-PCU meetings. There are three main theories used: interactional styles, gender, and chairpersons and their roles in a ...
Cinantya, A. (Anila)   +1 more
core  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Male Character's Gender Roles and Gender Development in Yaoi Manga Aozora No Sunda Iro Wa [PDF]

open access: yes, 2014
One genre that has been growing rapidly in manga is yaoi, which sells romance between beautiful young boys and men. In Aozora no Sunda Iro wa, I want to reveal how Sugiura takes female role in his same-sex romantic relationship and why Sugiura has ...
Meilinda, M. (Meilinda)   +1 more
core  

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