Results 41 to 50 of about 72,945 (287)

TLR Agonist Nano Immune Therapy Clears Peritoneal and Systemic Ovarian Cancer

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Intraperitoneal administration of immunogenic Toll‐like receptor agonist‐modified mesoporous silica nanoparticles leads to rapid internalization by ascites myeloid cells with trafficking to fat‐associated lymphoid clusters. Activation of myeloid cells counters suppressive immune mechanisms associated with peritoneal metastasis, leading to regional and ...
Ben Marwedel, Henning De May, Lauren Anderson, Lorél Y. Medina, Ellie Kennedy, Erica Flores, John O'Rourke, Marian Olewine, Irina Lagutina, Lillian Fitzpatrick, Fred Shultz, Donna F. Kusewitt, Eric Bartee, Sarah Adams, Achraf Noureddine, Rita E. Serda   +15 more
wiley   +1 more source

High and low contraceptive use amongst male young offenders: a qualitative interview study [PDF]

, 2014
<b>Objectives</b> There are high rates of fatherhood and sexually transmitted infections (STIs) among young incarcerated men. Here we focus on a sample of men incarcerated in a Scottish Young Offender Institution, analysing their accounts of ...
Buston, Katie, Parkes, Alison, Wight, Danny   +2 more
core   +1 more source

Delivery of Islatravir via High Drug‐Load, Long‐acting Microarray Patches for the Prevention or Treatment of Human Immunodeficiency Virus

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Islatravir‐loaded dissolving microarray patches (MAPs) provide a minimally invasive, long‐acting solution for HIV‐1 prevention and treatment. In rats, sustained islatravir delivery lasts up to three months, while in minipigs, efficacious plasma levels are detected for six days.
Qonita Kurnia Anjani, Ashley R. Johnson, Akmal H. Sabri, Ryan Lutz, Steven Tignor, Jeanine Ballard, Nathan Rudd, Li Zhao, Lalitkumar K. Vora, Stephanie E. Barrett, Angela Wagner, Ryan F. Donnelly   +11 more
wiley   +1 more source

Condom use at last sex by young men in Ethiopia: the effect of descriptive and injunctive norms

Reproductive Health, 2018
Background Condoms are an important prevention method in the transmission of HIV and sexually transmitted infections as well as unintended pregnancy.
Aparna Jain, Elizabeth Tobey, Hussein Ismail, Annabel Erulkar   +3 more
doaj   +1 more source

Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A novel subcutaneous formulation combining alpha‐ketoglutarate, glycolysis inhibitor PFK15, and a myelin peptide reduces inflammation in a mouse TBI model. This formulation promotes regulatory immune cells, enhances autophagy, and improves motor function, suggesting its potential as a prophylactic immunosuppressive therapy to mitigate TBI‐induced ...
Kelly Lintecum, Abhirami Thumsi, Kara Dunn, Lindsey Druschel, Sierra Chimene, David Flores Prieto, Amberlyn Simmons, Shivani Mantri, Arezoo Esrafili, Srivatsan J. Swaminathan, Mytreyi Trivedi, Shreya Anandan, Crystal Willingham, Alondra Davila, Sahil Inamdar, Joslyn L. Mangal, Abhirami P. Suresh, Niveda M. Kasthuri, Madan Mohan Chandra Sekhar Jaggarapu, Nicole Appel, Taravat Khodaei, Nathan D. Ng, Alison Sundem, Sanmoy Pathak, George Bjorklund, Jason Newbern, Jeffrey Capadona, Sarah E. Stabenfeldt, Abhinav P. Acharya   +28 more
wiley   +1 more source

Reasons for Not Using Condoms by People Who Inject Drugs in Iran; Results from a Conventional Content Analysis in 2018

مجله اپیدمیولوژی ایران, 2021
Background and Objectives: This qualitative study was conducted to identify reasons for not using condoms by people who inject drugs (PWID) in Iran.
M Faghir Gangi, Ali Mirzazadeh, H Rastad, S Nedjat, A Rahimi-Movaghar, K Yazdani   +5 more
doaj  

Knowledge and attitudes on contraceptives among undergraduates in the state universities of the Western Province

Journal of the College of Community Physicians, 2019
Objective: To describe knowledge and attitudes on contraceptives among undergraduates in the state universities of the Western Province Methods: A descriptive cross sectional study was conducted among 1575 second and third year undergraduates using ...
Upuli Perera, chrishantha Abeysena
doaj   +1 more source

Two heads are better than one: The association between condom decision-making and condom use errors and problems [PDF]

, 2008
This is an open access article - Copyright @ 2008 BMJ Publishing GroupObjectives: This exploratory study compared the frequency of condom use errors and problems between men reporting that condom use for penile–vaginal sex was a mutual decision compared ...
Crosby, RA, Graham, CA, Milhausen, R, Sanders, SA, Yarber, WL   +4 more
core   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Examining the place of the female condom in India’s family planning program: A qualitative investigation of the attitudes and opinions of key stakeholders in Pune, India

BMC Public Health, 2022
Background With overpopulation contributing to the depletion of planetary resources, the high rates of unintended pregnancies in India are a cause for concern.
Medhavi Weerasinghe, Shubhangi Agawane, Neelima Karandikar, Jane Fisher, Jayagowri Sastry   +4 more
doaj   +1 more source