Results 51 to 60 of about 72,945 (287)

Smarter Programming of the Female Condom: Increasing Its Impact on HIV Prevention in the Developing World [PDF]

, 2008
The purpose of this study was to investigate the relative value of the female condom for HIV prevention within heterosexual relationships in the developing world.
Elliot Marseille, James G. Kahn, Kyle Peterson, Laura Herman   +3 more
core  

Lycium barbarum Glycopeptide Alleviates Neomycin‐Induced Ototoxicity by Inhibiting Tryptophan Hydroxylase‐Mediated Serotonin Biosynthesis

Advanced Science, EarlyView.
Lycium barbarum glycopeptide (LBGP), which is further extracted from Lycium barbarum polysaccharides, exhibits significant protective effects against neomycin‐induced hearing dysfunction including oxidative stress in cochlea and loss of key cells in cochlea.
Yunhao Wu, Li Zhang, Shengda Cao, Jingwen Zhang, Cheng Li, Yunlong Shan, Qiuping Liu, Zhexiong Yu, Qiaojun Fang, Yuhua Zhang, Xiaolong Fu, Kwok‐Fai So, Renjie Chai   +12 more
wiley   +1 more source

Inhibition of RACK1‐Mediated NLRP3 Oligomerization (Active Conformation) Ameliorates Acute Respiratory Distress Syndrome

Advanced Science, EarlyView.
Schematic diagram showing the potential mechanism of bigelovin on the activation of NLRP3 inflammasome Bigelovin may inhibit activated protein C kinase 1 (RACK1) by directly binding with cys168 of RACK1. Bigelovin thus prevents oligomerization of NLRP3 (NLRP3 active conformation) and subsequent assembly of NLRP3 inflammasome, blocking the activation of
Jian Cui, Meng Yang, Chengli Yu, Haidong Zhang, Yuan Gong, Yang Hu, Yue Wang, Qingxin Yuan, An Pan, Jiepin Li, Yaowen Hu, Zecheng Jin, Xuemei Peng, Anyuan Wu, Junwei Wang, Qian Wang, Yinan Zhang, Lihong Hu   +17 more
wiley   +1 more source

The levels and factors associated with inconsistent condom use among young males with older, same-sex partners in South Africa

Cogent Social Sciences, 2020
Condom use among females with older, male sexual partners is well documented in South Africa. To a far lesser extent, condom use among males with older same-sex partners is known.
Nicole De Wet-Billings, Brendon K. Billings   +1 more
doaj   +1 more source

Sexual Activities and Changes in Condom Use in Group Sex Events Among Female Sex Workers in Melbourne, Australia

Frontiers in Public Health, 2022
BackgroundThere are few studies investigating group sex among female sex workers (FSWs). This study aimed to examine the typical number of group sex participants, sexual activities and condom use in group sex among FSWs attending a sexual health clinic ...
Chen Lew, Chen Lew, Christopher K. Fairley, Christopher K. Fairley, Julien Tran, Julien Tran, Tiffany R. Phillips, Tiffany R. Phillips, Ei T. Aung, Ei T. Aung, Kate Maddaford, Marcus Y. Chen, Marcus Y. Chen, Catriona S. Bradshaw, Catriona S. Bradshaw, Catriona S. Bradshaw, Eric P. F. Chow, Eric P. F. Chow, Eric P. F. Chow   +18 more
doaj   +1 more source

Multi-Country Study on Trusted Partners among Youth: Eritrea, Tanzania, Zambia, and Zimbabwe [PDF]

, 2002
ObjectivesExplore youth's definitions of "trust"Establish criteria youth use to determine the trustworthiness of partnersIdentify types of individuals youth believe they can and cannot "trust"Examine trust's influence on sexual decision-making and STI ...
John Berman, Kim Longfield, Megan Klein
core  

AhR‐Dependent Induction of β‐Defensin 1 in Colonic Epithelial Cells Regulates Cross‐Talk between Gut Microbiota and Immune Response Leading to Attenuation of Colitis

Advanced Science, EarlyView.
This study identifies a key signaling pathway involving the environmental sensor AhR and antimicrobial peptides, such as BD‐1, in the regulation of intestinal homeostasis. It highlights the role of BD‐1 in regulating gut microbiota and the intestinal immune response.
Manikandan Palrasu, Amarnath Marudamuthu, Khadija Kakar, Hamida Hamida, Shruthi Thada, Rohan Gupta, Kiesha Wilson, Taylor Carter, Yin Zhong, Archana Saxena, Xiaoming Yang, Narendra Singh, Philip Brandon Busbee, Jie Li, Monica Garcia‐Buitrago, Prakash Nagarkatti, Mitzi Nagarkatti   +16 more
wiley   +1 more source

Condom negotiation, HIV testing, and HIV risks among women from alcohol serving venues in Cape Town, South Africa. [PDF]

PLoS ONE, 2012
Women in South Africa are at particularly high-risk for HIV infection and are dependent on their male partners' use of condoms for sexual risk reduction. However, many women are afraid to discuss condoms with male partners, placing them at higher risk of
Eileen V Pitpitan, Seth C Kalichman, Demetria Cain, Lisa A Eaton, Kate B Carey, Michael P Carey, Ofer Harel, Leickness C Simbayi, Vuyelwa Mehlomakhulu, Kelvin Mwaba   +9 more
doaj   +1 more source

"Condoms Are Reliable but I Am Not": A Qualitative Analysis of AIDS-Related Beliefs and Attitudes of Young Heterosexual Adults in Budapest, Hungary and St. Petersburg, Russia [PDF]

, 2006
HIV and STD prevention is an essential component of public health initiatives in countries throughout Central and Eastern Europe. Liberalization in sexual values, declining age at first sex, higher levels of sexual activity, and inconsistent condom use
, , , Bauer, Bukodi, Dehne, Dési, Engleman, Federal Service, HIV Infection, Hungarian Central, Lunin, Morris, Morse, Perlez, Pokrovsky, Pokrovsky VV, The, Tsybakova DA, UNAIDS   +19 more
core   +1 more source

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen   +11 more
wiley   +1 more source