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Nature Reviews Disease Primers, 2023 Clinical infertility is the inability of a couple to conceive after 12 months of trying. Male factors are estimated to contribute to 30-50% of cases of infertility. Infertility or reduced fertility can result from testicular dysfunction, endocrinopathies, lifestyle factors (such as tobacco and obesity), congenital anatomical factors, gonadotoxic ...
Michael Eisenberg +2 more
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Nature Reviews Urology, 2018
Male infertility is a multifactorial pathological condition affecting approximately 7% of the male population. The genetic landscape of male infertility is highly complex as semen and testis histological phenotypes are extremely heterogeneous, and at least 2,000 genes are involved in spermatogenesis.
Csilla Gabriella Krausz +1 more
exaly +3 more sources
Male infertility is a multifactorial pathological condition affecting approximately 7% of the male population. The genetic landscape of male infertility is highly complex as semen and testis histological phenotypes are extremely heterogeneous, and at least 2,000 genes are involved in spermatogenesis.
Csilla Gabriella Krausz +1 more
exaly +3 more sources
The Lancet, 2021
It is estimated that infertility affects 8-12% of couples globally, with a male factor being a primary or contributing cause in approximately 50% of couples. Causes of male subfertility vary highly, but can be related to congenital, acquired, or idiopathic factors that impair spermatogenesis.
Ashok, Agarwal +8 more
openaire +3 more sources
It is estimated that infertility affects 8-12% of couples globally, with a male factor being a primary or contributing cause in approximately 50% of couples. Causes of male subfertility vary highly, but can be related to congenital, acquired, or idiopathic factors that impair spermatogenesis.
Ashok, Agarwal +8 more
openaire +3 more sources
Best Practice & Research Clinical Obstetrics & Gynaecology, 2003
Infertility affects 13-18% of couples and growing evidence from clinical and epidemiological studies suggests an increasing incidence of male reproductive problems. The pathogenesis of male infertility can be reflected by defective spermatogenesis due to pituitary disorders, testicular cancer, germ cell aplasia, varicocele and environmental factors or ...
E, Iammarrone +4 more
openaire +2 more sources
Infertility affects 13-18% of couples and growing evidence from clinical and epidemiological studies suggests an increasing incidence of male reproductive problems. The pathogenesis of male infertility can be reflected by defective spermatogenesis due to pituitary disorders, testicular cancer, germ cell aplasia, varicocele and environmental factors or ...
E, Iammarrone +4 more
openaire +2 more sources
Journal of Urology, 2007
We assessed male infertility and its treatment in the United States by identifying trends in the use of health care resources and estimating the economic impact of such care.The analytical methods used to generate these results were previously described.Inpatient hospitalizations for male infertility were relatively few with an overall rate of 0.9/100 ...
Randall B, Meacham +4 more
openaire +2 more sources
We assessed male infertility and its treatment in the United States by identifying trends in the use of health care resources and estimating the economic impact of such care.The analytical methods used to generate these results were previously described.Inpatient hospitalizations for male infertility were relatively few with an overall rate of 0.9/100 ...
Randall B, Meacham +4 more
openaire +2 more sources
Hemochromatosis and male infertility
Obstetrics & Gynecology, 1998The clinical association of hemochromatosis and infertility is rare. Hemochromatosis may affect fertility through a variety of mechanisms.A 44-year-old man and his 36-year-old wife presented with primary infertility of 7 years' duration. The husband was diagnosed as having idiopathic hemochromatosis, abnormal glucose tolerance, and hypogonadism ...
S, Oehninger, I, Pike, N, Slotnick
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Immunobiology of male infertility
Human Reproduction, 1988Experimental and clinical data reported in the literature emphasize the important role that immune factors may play in the genesis of male infertility even if many problems still remain to be solved. Auto or homo-sensitization in animals (and in male volunteers) can be obtained with testicular homogenate or epididymal spermatozoa and complete Freund's ...
ISIDORI, Aldo +2 more
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Salicylazosulfapyridine and male infertility
European Journal of Obstetrics & Gynecology and Reproductive Biology, 1981Recently, several reports have suggested that salicylazosulfapyridine causes a reduction in semen quality in patients with ulcerative colitis. After withdrawal of the drug pregnancies have been reported. The aim of this report is to offer additional data to the discussion on the deleterious effect of salicylazosulfapyridine on semen quality.
M J, Heineman, J M, Dony, R, Rolland
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The Genetics of Male Infertility
Journal of Urology, 1996We provide an up-to-date summary of the genetic aspects of male infertility.The literature on male infertility was extensively reviewed.Genetic defects are associated with a variety of clinical presentations by the infertile man ranging from gonadotropin-releasing hormone deficiency to spermatogenic failure to obstructive azoospermia.
V, Mak, K A, Jarvi
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Testosterone and Male Infertility
Urologic Clinics of North America, 2016Hypogonadism and its therapies have a significant impact on male fertility potential. It is necessary to determine the etiology to treat and counsel the patient appropriately on therapeutic options. For the hypogonadal male on exogenous testosterone, management should begin with cessation of the exogenous testosterone and supplemental subcutaneous ...
Samuel J, Ohlander +2 more
openaire +2 more sources