Results 271 to 280 of about 3,525,982 (384)

The role of SLC26A8 homozygous variants in male infertility and flagellum abnormalities

open access: gold
Bin Mao   +10 more
openalex   +1 more source

FSTL1 Orchestrates Metabolic‐Epigenetic Crosstalk: Glycolysis‐Dependent H3K18 Lactylation Drives Cartilage Fibrosis in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
FSTL1 promotes glycolysis during chondrocyte fibrosis by triggering the HIF‐1 signaling pathway, which causes lactate to accumulate. The buildup of lactate leads to changes in histone lysine lactylation, which in turn enhances the expression of genes associated with fibrosis.
Feng Lu   +12 more
wiley   +1 more source

Exploring Single-Nucleotide Polymorphisms in Primary and Secondary Male Infertility. [PDF]

open access: yesMed Sci (Basel)
Dahadhah FW   +4 more
europepmc   +1 more source

ASSOTIATION-GENETIC STUDY OF POLYMORPHISM G-105A SEPS1 GENE IN MALE INFERTILITY

open access: diamond, 2018
N. G. Kulchenkо   +2 more
openalex   +1 more source

Chronic PET‐Microplastic Exposure: Disruption of Gut–Liver Homeostasis and Risk of Hepatic Steatosis

open access: yesAdvanced Science, EarlyView.
Chronic exposure to environmentally relevant PET microplastics disrupts gut–liver homeostasis, leading to hepatic steatosis, early fibrosis, and altered gut microbiota. These effects signal metabolic imbalance and gut–liver axis impairment, emphasizing chronic microplastic ingestion as an emerging environmental health risk linked to non‐communicable ...
Surye Park   +5 more
wiley   +1 more source

Tubule‐Derived IFN‐α Promotes GSDMD‐Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation

open access: yesAdvanced Science, EarlyView.
Mao and colleagues uncover a STAT2/IRF9‐dependent signaling axis through which tubular epithelial cell (TEC)‐derived IFN‐α induces gasdermin D (GSDMD)‐mediated pyroptosis in macrophages. This TEC‐macrophage feedback loop amplifies renal inflammation and fibrosis, providing mechanistic insight into the progression of chronic kidney disease and revealing
Yiping Xu   +12 more
wiley   +1 more source

Unraveling a Subgroup of Men With Unexplained Male Infertility-Men With Normogonadotropic Nonobstructive Azoospermia.

open access: yesJ Clin Endocrinol Metab
Schwarzkopf V   +5 more
europepmc   +1 more source

Cracking the code: how piRNA pathway shapes spermatogenesis and combats male infertility. [PDF]

open access: yesFront Cell Dev Biol
Hong Z   +7 more
europepmc   +1 more source

A Set of Novel Venom Proteins Enables Parasitoid Wasps to Exploit Older Hosts and Coexist with Competitors

open access: yesAdvanced Science, EarlyView.
This study elucidates a molecular mechanism enabling species coexistence between parasitoid wasps, showing how Asobara japonica uses a set of novel venom proteins to delay host development and exploit older hosts, thereby achieving temporal niche partitioning with Leptopilina drosophilae. Abstract Interspecific competition can drive species coexistence
Junwei Zhang   +11 more
wiley   +1 more source

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