Results 111 to 120 of about 2,436,431 (290)

Nurse-Led Intervention to Reduce Parental Anxiety and Child Pain During Non-Therapeutic Male Circumcision: A Randomized Trial

open access: yesSAGE Open Nursing
Introduction Non-therapeutic male circumcision is often performed in outpatient settings and has physical and emotional implications for children and families.
Lyudmyla Andrusenko-Kalchenko PhD   +5 more
doaj   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

open access: yesAdvanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao   +5 more
wiley   +1 more source

Male Nurses’ Dealing with Tensions and Conflicts with Patients and Physicians: A Theoretically Framed Analysis

open access: yesJournal of Multidisciplinary Healthcare, 2020
Aimei Mao,1 Jialin Wang,2 Yuan Zhang,3 Pak Leng Cheong,1 Iat Kio Van,1 Hon Lon Tam1 1Kiang Wu Nursing College of Macau, Macau, People’s Republic of China; 2College of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan ...
Mao A   +5 more
doaj  

Underground Signals: The Ecological Power of Root Volatiles

open access: yesAdvanced Science, EarlyView.
Root volatiles mediate rhizosphere chemical communication, shaping interactions among plants, microbes, herbivores, and natural enemies. Their production, transport, and perception underpin ecological adaptation, multitrophic interactions, and plant resilience, offering opportunities for sustainable crop protection, resilient agroecosystems, and ...
Xueyao Cao   +31 more
wiley   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

open access: yesAdvanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang   +11 more
wiley   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo   +14 more
wiley   +1 more source

A history of nurse education and the clinical nurse educator

open access: yes, 2019
This chapter discusses the potential roles which will be engendered by the new Nursing and Midwifery Council standards and framework for nurse education. Woven throughout the account will be the clinical nurse educator roles which have fulfilled the need
Bill Whitehead, Whitehead, Bill
core   +1 more source

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

open access: yesAdvanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang   +12 more
wiley   +1 more source

Professional becoming of male nurses: a qualitative study in Lithuania

open access: yesInternational Journal of Qualitative Studies on Health & Well-Being
Purpose To reveal the features of Lithuanian male nurses’ professional becoming. Methods The participants were six men who had been working as nurses for over a year, and one man who had been formerly employed as a nurse for over a year.
Aušrinė Gribačiauskaitė   +1 more
doaj   +1 more source

TRAF6 Lactylation in Glycolytic Macrophages Drives NF‐κB Signaling and M1 Polarization During Orthodontic Tooth Movement

open access: yesAdvanced Science, EarlyView.
Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He   +9 more
wiley   +1 more source

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