Results 161 to 170 of about 2,436,431 (290)

SynNotch Receptors for Visualizing Immunoreceptor Force Transmission and Downstream Signaling In Vivo

Advanced Science, EarlyView.
A mechanically activated SynNotch reporter platform enables detection of force transmission through receptors as they mediate immune cell interactions. Targeting CD40 on B cells and TCR on T cells records force‐induced reporter activation across 2D coculture, 3D organoid, and implanted in mice, which also reveal force‐amplification of immune receptor ...
Menglan Li, Jintian Lyu, Kaitao Li, Ameya Dravid, Deepali Balasubramani, Amir H. K. Ashkezari, Hyun‐Kyu Choi, Gabriel A. Kwong, Ankur Singh, Cheng Zhu   +9 more
wiley   +1 more source

Effect of a Nurse-Navigated Game-Based Program on Transition Readiness and Psychosocial Outcomes in Adolescents With Osteosarcoma: A Cluster-Nonrandomized Controlled Study. [PDF]

Psychooncology
Ma J, Zhang X, Li J, Liu F.
europepmc   +1 more source

Watercolours of New Zealand subjects [7] [picture] /

Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an10543540 ...
Male, R., Rev.
core  

p300‐Mediated H3K18 Lactylation Drives Radiation‐Induced Pulmonary Fibrosis via VIRMA‐Dependent m6A Modification of GATA3

Advanced Science, EarlyView.
Radiation triggers glycolytic reprogramming in alveolar epithelial type II cells, causing pathological lactate accumulation. This metabolic stress drives p300‐mediated H3K18 lactylation at the VIRMA promoter, activating transcription. Elevated VIRMA enriches m6A on GATA3 mRNA, which YTHDF1 stabilizes, ultimately driving epithelial–mesenchymal ...
Junxuan Yi, Mingwei Wang, Duo Yu, Mingqi Zhao, Xinyan Wang, Shiqi Li, Xiaowen Han, Wei Wei, Shunzi Jin   +8 more
wiley   +1 more source

Humanistic Care Needs of Elderly Chronic Disease Inpatients from the Perspective of Patient Journey Mapping: A Qualitative Study. [PDF]

Patient Prefer Adherence
Zhao J, Zhang Y, Bai G, Wu Y, Xue T, Wang Y.   +5 more
europepmc   +1 more source

Watercolours of New Zealand subjects [3] [picture] /

Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an10543540 ...
Male, R., Rev.
core  

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

Advanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan, Lixin Tian, Lianjie Peng, Jingyu Zhang, Lining Lin, Xiaoting Zhang, Yaxian Luo, Zhichao Liu, Xinhua Yao, Mouyuan Sun, Yong He, Mengfei Yu, Huiming Wang   +12 more
wiley   +1 more source

Workplace Violence Experiences Among Nurse Educators in Saudi Arabia: A Qualitative Descriptive Study. [PDF]

Nurs Open
Salvador JT, Almahmoud SA, Al-Dossary RNM, Al-Anazi BMM, Alqahtani FM, Al-Otaibi A, Ramzi OI, Kamel NM, Aldhafeeri FL, Trinidad MA, Rosario AB, Ibrahim AM, Cabonce SG, Agman DD, Alfaraj EA.   +14 more
europepmc   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

Perceived decent work and work engagement among nurses: a multicenter cross-sectional mediation analysis of self-esteem. [PDF]

Front Public Health
Liu J, Lin T, Zhang T, Yang B, Zeng Q.
europepmc   +1 more source