Results 181 to 190 of about 315,538 (296)

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

open access: yesAdvanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters   +12 more
wiley   +1 more source

Conversion of elite bread wheat cultivars HD3086 and HD2932 into cytoplasmic male sterile (CMS) lines and their genetic assessment to develop CMS-based hybrids. [PDF]

open access: yesBMC Plant Biol
Malik AS   +10 more
europepmc   +1 more source

Dynamic Self‐Clickable Decellularized Matrix Hydrogels for Regulating Vascularity and Enhancing Muscle Regeneration

open access: yesAdvanced Science, EarlyView.
Dynamic decellularized hydrogels are prepared using bovine decellularized small intestine submucosa (SIS) norbornene (dSIS‐NB). Bovine dSIS contained significant amounts of disulfide‐rich fibrillin‐I, enabling ‘self‐clickable’ thiol‐norbornene gelation and spatiotemporal tuning of hydrogel physicochemical properties.
Van Thuy Duong   +4 more
wiley   +1 more source

Dual‐Network Protein Hydrogels Promote Rapid Hemostasis and Immune‐Regulated Scarless Tissue Regeneration

open access: yesAdvanced Science, EarlyView.
A dual‐network protein hydrogel substantially improves hemostasis and scar‐free healing.The adaptive network maintains intimate tissue contact while providing strong wet adhesion, tunable mechanics, and controlled degradation. Concurrent ROS scavenging and M2 polarization suppress fibrotic pathways, preventing scar formation.
Xiaomei Li   +11 more
wiley   +1 more source

Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair

open access: yesAdvanced Science, EarlyView.
Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li   +9 more
wiley   +1 more source

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