Results 241 to 250 of about 315,538 (296)

AI‐Designed Cyclic Peptides Enable Controllable Modulation of the CD28 Immune Checkpoint

Advanced Science, EarlyView.
AI‐designed cyclic peptides enable controllable modulation of the CD28 immune checkpoint through reversible disruption of CD28‐CD80/CD86 interactions. The lead peptide, CIP‐3, suppresses T‐cell activation without intrinsic agonist activity, demonstrates dose‐dependent efficacy in a murine colitis model, and attenuates inflammatory cytokine production ...
Katarzyna Kuncewicz, Saurabh Upadhyay, Renjie Zhu, Hongliang Duan, Moustafa T. Gabr   +4 more
wiley   +1 more source

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

Advanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv, Xuejie Cai, Yiming Xu, Xingdong Yang, Ruoying Wang, Han Wang, Yixin Bian, Jiawei Xu, Jiao Lu, Lulu Liu, Yingjie Wang, Jibin Song, Bin Feng, Xisheng Weng   +13 more
wiley   +1 more source

Identification of heterosis and combining ability in the hybrids of male sterile and restorer sorghum [Sorghum bicolor (L.) Moench] lines. [PDF]

PLoS One
Zhang Y, Chen J, Gao Z, Wang H, Liang D, Guo Q, Zhang X, Fan X, Wu Y, Liu Q.   +9 more
europepmc   +1 more source

Transcriptomic Profiling of Two Rice Thermo-Sensitive Genic Male Sterile Lines with Contrasting Seed Storability after Artificial Accelerated Aging Treatment. [PDF]

Plants (Basel)
Li F, Ye H, Wang Y, Zhou J, Zhang G, Liu X, Lu X, Wang F, Chen Q, Chen G, Xiao Y, Tang W, Deng H.   +12 more
europepmc   +1 more source

Commercial suitability and characterization of newly developed Erucastrum canariense (Can) sterile cytoplasm based cytoplasmic male sterile (CMS) lines in Indian cauliflower. [PDF]

Sci Rep
Manjunath KS, Singh S, Kalia P, Mangal M, Sharma BB, Singh N, Ray M, Rao M, Tomar BS.   +8 more
europepmc   +1 more source

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Male Sterility

2004
National ...
Budar, Francoise, Delourme, Régine, Pelletier, G.   +2 more
openaire   +2 more sources

Male Sterilization

Clinics in Obstetrics and Gynaecology, 1979
This review of recent information and advances in the area of male sterilization deals with recent epidemiologic studies that discuss potential ill effects hypothesized to be a result of vasectomy, including carcinoma of the prostate and carcinoma of the testicle. Rebuttals to these hypotheses are presented.
openaire   +4 more sources

A male-sterile insertion in the mouse

Cytogenetics and Cell Genetics, 2008
Is(7;l)40H was found in the daughter of a male mouse given spermatozoal X-irradiation. It is a non-inverted insertion of about half of chromosome 7 into chromosome 1, generating a long somatic marker chromosome. Breakpoints are in bands IB, 7B1, and 7F1; linkage tests show that these breakpoints are about midway between fz and In on the 1, and 0.2 ...
Searle, A.G., Beechey, C.V., de Boer, P., de Rooij, D.G., Evans, E.P., Kirk, M.   +5 more
openaire   +4 more sources