Results 121 to 130 of about 88,045 (297)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Additional file 11: of The initial deficiency of protein processing and flavonoids biosynthesis were the main mechanisms for the male sterility induced by SX-1 in Brassica napus

, 2018
Luyun Ning, Zhiwei Lin, Jianwei Gu, Lu Gan, Yonghong Li, Hao Wang, Liyun Miao, Libin Zhang, Baoshan Wang, Maoteng Li   +9 more
openalex   +1 more source

Ultrasound in Women's Health: Mechanisms, Applications, and Emerging Opportunities

Advanced Materials, EarlyView.
As healthcare moves toward decentralization, ultrasound technologies are evolving from strictly imaging tools in clinical settings into versatile diagnostic and therapeutic platforms, with growing roles addressing women's health needs. This review highlights how ultrasound's underlying physical mechanisms can be harnessed to reduce disparities in women'
Sarah B. Ornellas, Bilal Kizilaslan, Aastha Shah, Jason F. Hou, Yoonsoo Shin, Alejandra Hernandez Moyers, Claudia Lozano, Canan Dagdeviren   +7 more
wiley   +1 more source

Correction: Mutant conferring partial male sterility: a versatile system for unrestrained hybridization in a highly autogamous finger millet crop [PDF]

GANIGER MANJAPPA, Gowda M.V.C., S. Rangaiah, V. Sujay   +3 more
openalex   +1 more source

Incorporating male sterility increases hybrid maize yield in low input African farming systems [PDF]

, 2022
Sarah Collinson, Esnath Hamdziripi, Hugo De Groote, Michael Ndegwa, Jill E. Cairns, Marc C. Albertsen, Dickson Ligeyo, Kingstone Mashingaidze, M. Olsen   +8 more
openalex   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Cytoplasmic male sterility in Brassicaceae crops

, 2014
Hiroshi Yamagishi, S. R. Bhat
openalex   +2 more sources

Diploid Male Gametes Circumvent Hybrid Sterility Between Asian and African Rice Species

, 2020
Daichi Kuniyoshi, Itaru Masuda, Yoshitaka Kanaoka, Yuki Shimazaki-Kishi, Yoshihiro Okamoto, Hideshi Yasui, Toshio Yamamoto, Kiyotaka Nagaki, Yoichiro Hoshino, Yohei Koide, Itsuro Takamure, Yuji Kishima   +11 more
openalex   +1 more source

Two‐Photon Polymerized Microvascular Environments for Multicellular Modeling of the Blood–Brain Tumor Barrier

Advanced Materials Technologies, EarlyView.
Modeling the blood–brain tumor barrier is challenging due to complex interactions between brain microvasculature and glioma cells. We present two‐photon polymerized 3D micro‐porous capillary‐like structures that support endothelial alignment, cytoskeletal organization, and pericyte‐endothelial‐glioma tri‐cultures.
Nastaran Barin, Sayba Z. Chowdhury, Maurice de Wit, Rania Head, Kiki Bals, Erwin Brosens, Marvin M. van Luijn, Hayri E. Balcioglu, Angelo Accardo, Pim J. French   +9 more
wiley   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source