Results 151 to 160 of about 88,045 (297)

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

Advanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu, Hongzhi Li, Xiang Li, Chunxiu Du, Ting Wang, Xuling Zhou, Xiaobei Xie, Yunxia Shao, Yingzhi Huang, Yanling Hu, Xinxin Guo, Bin Zhu, Shanshan Yu, Xiaoyan Zhang, Binghai Zhao   +14 more
wiley   +1 more source

Insights into the Molecular Basis of Pollen Coat Development and Its Role in Male Sterility. [PDF]

Int J Mol Sci
Lyu B, Liang C.
europepmc   +1 more source

Association of nad7a Gene with Cytoplasmic Male Sterility in Pigeonpea [PDF]

, 2015
Pallavi Sinha, K. B. Saxena, Rachit K. Saxena, Vikas Kumar Singh, V. Suryanarayana, C.V. Sameer Kumar, Mohan A. V. S. K. Katta, Aamir W. Khan, Rajeev K. Varshney   +8 more
openalex   +1 more source

IL1R2 Marks and Sorts a Spermatogonial Stem Cell Population Critical for Restoring Spermatogenesis Upon Interruption in Mammals

Advanced Science, EarlyView.
Spermatogonial stem cells (SSCs) provide critical support to spermatogenesis. Here, the author established Il1r2 as a sorting marker for SSCs, with which further insights into the SSC heterogeneity and dynamic features can be obtained. They also confirmed findings in both mouse and human, thus validating IL1R2 as the surface marker for isolating and ...
Pengyu Li, Zexuan Zhang, Zihan Xie, Cheng Jin, Zhipeng Wang, Changwei Yuan, Jun Zhu, Jielin Tang, Mengzhen Li, Dingfeng Zou, Xinyu Mang, Jun Liu, Dingyao Chen, Qi Geng, Yan Lu, Ning Zhang, Shiying Miao, Jing Peng, Kai Li, Wei Song   +19 more
wiley   +1 more source

Advances in Cytoplasmic Male Sterility in Sugar Beet from Mitochondrial Genome Structural Dynamics and Nuclear-Cytoplasmic Coordination. [PDF]

Int J Mol Sci
Zhong W, Zhang S, Gu X, Zhao Y, Wu Z, Liu D, Xing W.   +6 more
europepmc   +1 more source

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang, Jianbo Huang, Shuwei Zhang, Sujiao Cao, Fangxue Du, Liqiang Zhou, Li Qiu, Yuanjiao Tang   +7 more
wiley   +1 more source

Mitochondrial polymorphism of sea beet (Beta vulgaris ssp. maritima), a species with cytoplasmic male sterility. [PDF]

PLoS One
Murata T, Kagami-Katsuyama H, Oishi M, Tanaka H, Sano C, Kashikura J, Hayakawa R, Kubota K, Taniguchi E, Suzuki K, Kitazaki K, Kubo T.   +11 more
europepmc   +1 more source

MutS HOMOLOG1 silencing mediatesORF220substoichiometric shifting and causes male sterility inBrassica juncea [PDF]

, 2015
Na Zhao, Xinyue Xu, Yashitola Wamboldt, Sally A. Mackenzie, Xiaodong Yang, Zhongyuan Hu, Jinghua Yang, Mingfang Zhang   +7 more
openalex   +1 more source

Long‐Term Effects of Xenotransplantation of Human Enteric Glia in an Immunocompetent Rat Model of Acute Brain Injury

Advanced Science, EarlyView.
Acute brain injuries are characterized by extensive tissue damage, resulting in debilitating deficits in patients. Despite considerable progress, cell‐based approaches have yet to identify an ideal candidate. This long‐term study explores the use of an untested cell source – human enteric glia – and a non‐invasive administration route – intranasal ...
Nina Colitti, Edwige Rice, Franck Desmoulin, Maylis Combeau, Mélissa Parny, Lorenne Robert, Etienne Buscail, Barbara Bournet, Nathalie Vergnolle, Isabelle Raymond‐Letron, Isabelle Loubinoux, Carla Cirillo   +11 more
wiley   +1 more source

The Arabidopsis MALE STERILITY 2 protein shares similarity with reductases in elongation/condensation complexes [PDF]

, 1997
Mark G. M. Aarts, Rachel Hodge, Kriton Kalantidis, Dion E. A. Florack, Zoe A. Wilson, B. J. Mulligan, Willem J. Stiekema, Rod Scott, Andy Pereira   +8 more
openalex   +1 more source