Results 151 to 160 of about 2,022,963 (289)

CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano, Allen C. Luo, Paul Taufalele, Jenna A. Dombroski, Ehsan Aalaei, Schyler J. Rowland, Melissa S. Cantú, Alexandria T. Carter, Samantha V. Knoblauch, Cynthia A. Reinhart‐King, Michael R. King   +10 more
wiley   +1 more source

Redundant Glycerol-3-Phosphate Acyltransferases Regulate Thermo-Sensitive Genic Male Sterility in Rice. [PDF]

Plant Biotechnol J
Cheng S, Zheng H, Tian Y, Wang C, Yu X, Dong K, Wang J, Lu J, Chen K, He X, Shao K, Gao J, Yao B, Hu Y, Xie Z, He L, Xie Z, Zhu Y, Guo S, Lei D, Jian A, Zhu X, Yu H, Zhang S, Chen M, Chen Y, Jiang L, Ren Y, Guo X, Liu S, Liu X, Zhu S, Zhao Z, Wan J.   +33 more
europepmc   +1 more source

Targeted Degradation of STING by a Neutrophil Membrane‐Coated Nanoplatform Suppresses Microglial Pyroptosis After Subarachnoid Hemorrhage

Advanced Science, EarlyView.
MG1@NM‐Px serves as a microglia‐targeted STING‐degrading nanoplatform for subarachnoid hemorrhage. Following systemic administration, it crosses the blood–brain barrier and accumulates in activated microglia. STP1‐mediated STING ubiquitination and degradation suppress MAPK/inflammasome signaling, GSDME‐mediated pyroptosis, and IL‐1β release, revealing ...
Ruotian Zhang, Kaikun Yuan, Haoyu Zou, Hanfeng Qin, Jiale Liu, Jianda Sun, Feifan Zhang, Yuankui Wang, Tong Wang, Jiaxing Dai, Chunxu Li, Yichi Chen, Yingfeng Tu, Huaizhang Shi   +13 more
wiley   +1 more source

Beyond the Prdm9 model: independent evolution of hybrid male sterility in house mice. [PDF]

Heredity (Edinb)
Klusáčková P, Woźniewska A, Dufková P, Dumont BL, Wójcik JM, Piálek J.   +5 more
europepmc   +1 more source

Diversification of male sterility sources in hybrid breeding programme

, 2017
Wild relatives accessions are crossed with the cultivated types and the derived populations are searched for the expression of male sterility traits. The identified male sterile are tested for the stability of the sterility expression.
Sameer Kumar, Chanda Venkata
core  

Histone H3K18 Lactylation Promotes the Malignant Progression of Wilms Tumor via a PSRC1/AKT/HIF‐1α Positive Feedback Loop

Advanced Science, EarlyView.
In nephroblastoma, aberrant glycolysis drives lactate accumulation, which elevates histone H3K18 lactylation via p300. Lactylation of the PSRC1 promoter activates its transcription. PSRC1 competitively binds AKT, relieving PTEN‐mediated inhibition and triggering AKT/mTOR/HIF‐1α signaling.
Yanping Wang, Hongjie Gao, Bifei Zhang, Xuetian Li, Ding Li, Aihua Cao, Fengyin Sun   +6 more
wiley   +1 more source

Enhancement of Male Sterility Stability in <i>Indica</i> Rice by Dual Thermo-Sensitive Genic Male Sterile Genes. [PDF]

Plants (Basel)
Wu M, Ji C, Ling B, Yang S, Yang J, Sun D, Zhong M, Wang F, Zou W, Zhu Y.   +9 more
europepmc   +1 more source

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

Advanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li, Zongqing Lu, Pu Fang, Qingqing Pang, Xianghui Wu, Bo Wang, Min Liang, Jingjing Pan, Haobo Kong, Haijian Cai, Juanjuan Li, Jiaying Kang, Dongsheng Wang, Dunling Xia, Mengmeng Xu, Qinghai You   +15 more
wiley   +1 more source

Advances in the Mechanistic Study of Environment-Sensitive Genic Male Sterility in Rice. [PDF]

Rice (N Y)
Wang D, Xie H, Zhang Y, Zhang M, Tang X, Yu Y, Zhu M.   +6 more
europepmc   +1 more source

Male Sterility [PDF]

Nature, 1954
openaire   +1 more source