Results 251 to 260 of about 3,297,329 (340)

Constitutive Androstane Receptor in Macrophages Regulates Toll‐Like Receptor 4‐Mediated Innate Immune Responses Against Endotoxemic Liver Injury

Advanced Science, EarlyView.
The present study uncovers a novel role of constitutive androstane receptor (CAR) in inflammation‐mediated damage. CAR activation in macrophages inhibits proinflammatory macrophages by interacting with Tlr4, which protects against endotoxemic liver injury.
Renjie Cao, Tingting Zhao, Ying Wang, Shaofei Song, Yuan Li, Mengling Hou, Yanxin Zhang, Sengpeng Wong, Siqi Wang, Yuran Wang, Hong Peng, Min Huang, Yiming Jiang   +12 more
wiley   +1 more source

Real‐Time Tracking of ASCT2‐Mediated Glutamine Uptake in Living Tumors With a Bioorthogonal Bioluminescent Probe

Advanced Science, EarlyView.
A bioluminescent probe, BLGLN, comprising BL568 and ASCT2‐uptaken AA201, enables real‐time monitoring and evaluation of ASCT2‐mediated glutamine uptake rates in living tumors via Staudinger ligation, aiding tumor metabolism studies and targeted therapeutics.
Bing‐Jun Zhou, Ji‐Lei Zhao, Fan Yin, Wen‐Da Chen, Yi Sun, Ying‐Ying Ren, Yi‐Min Chen, Tian Xie, Chong Duan, Jian‐Liang Zhou   +9 more
wiley   +1 more source

Widespread male sterility and trioecy in androdioecious Mercurialis annua: Its distribution, genetic basis, and estimates of morph-specific fitness components. [PDF]

Am J Bot
Nguyen MT, Martignier T, Pannell JR.
europepmc   +1 more source

Inheritance and Behavior of Genic Male Sterility in Rice (Oryza Sativa, L.).

, 1972
Damkheong Chandrapanya
openalex   +2 more sources

RIPK1 Drives JAK1‐STAT3 Signaling to Promote CXCL1‐Mediated Neutrophil Recruitment in Sepsis‐Induced Lung Injury

Advanced Science, EarlyView.
This article examines the central role of RIPK1 in the pathogenesis of sepsis‐induced lung injury. It elucidates how RIPK1 initiates an inflammatory cascade by activating JAK1‐STAT3 signaling, leading to CXCL1‐mediated neutrophil infiltration. Importantly, it demonstrates that pharmacological inhibition of RIPK1 effectively attenuates inflammation and ...
Hao Sun, Xiya Li, Shenjia Gao, Yi Jiang, Xinyi Wu, Zhaoyuan Chen, Han Wu, Qing Hua, Rui Zu, Huaijiang Xiang, Ronen Ben‐Ami, Changhong Miao, Li Tan, Ying Li, Jun Wang, Wankun Chen   +15 more
wiley   +1 more source

Single-cell transcriptomic and cell‑type‑specific regulatory networks in Polima temperature-sensitive cytoplasmic male sterility of Brassica napus L. [PDF]

BMC Plant Biol
Li S, Zhang J, Chen C, Ali A, Wen J, Dai C, Ma C, Tu J, Shen J, Fu T, Yi B.   +10 more
europepmc   +1 more source

Mode of Inheritance of Irradiation Induced Dwarfism and Male Sterility in the Tomato, Lycopersicon Esculentum.

, 1975
Joseph Garofalo
openalex   +2 more sources

Nociceptive Nerve‐Derived CGRP Exacerbates Uterine Fibrogenesis in Adenomyosis by Promoting CD140b+ CD146+ Fibroblast Differentiation

Advanced Science, EarlyView.
This study investigates adenomyosis fibrosis in relation to nociceptive nerves. Nociceptive nerve‐secreted CGRP promotes RAMP1hi CD140b+ CD146+ fibroblast differentiation into myofibroblasts through ERK activation, causing severe fibrosis. Rimegepant‐induced CGRP/RAMP1 signaling blockade alleviates fibrosis and restores fertility in a mouse model. This
Zi Ye, Anning Zhao, Xia Li, Yanqing Hao, Dong Huang, Jianmin Chen, Tiantian Li, Yangyang Dai, Wenchao Sun, Lie Ma, Songying Zhang, Liaobing Xin   +11 more
wiley   +1 more source

Author Correction: A natural mutation in the promoter of Ms-cd1 causes dominant male sterility in Brassica oleracea. [PDF]

Nat Commun
Han F, Yuan K, Sun W, Zhang X, Liu X, Zhao X, Yang L, Wang Y, Ji J, Liu Y, Li Z, Zhang J, Zhang C, Huang S, Zhang Y, Fang Z, Lv H.   +16 more
europepmc   +1 more source

Succinic Acid‐Induced Macrophage Endocytosis Promotes Extracellular Vesicle‐Based Integrin Beta1 Transfer Accelerating Fibroblast Activation and Sepsis‐Associated Pulmonary Fibrosis

Advanced Science, EarlyView.
Lipopolysaccharide (LPS) stimulates the production of succinic acid in lung tissue, which promotes macrophages endocytosis and the formation of multivesicular bodies (MVBs). These MVBs release profibrotic extracellular vesicles (EVs), facilitating the transfer of integrin beta1 (ITGβ1) transfer and subsequently activating fibroblasts, thereby ...
Wenyu Yang, Ri Tang, Yang Zhou, Jinquan Zhang, Shuya Mei, Yawen Peng, Xi Huang, Shunpeng Xing, Yuan Gao, Qiaoyi Xu, Zhengyu He   +10 more
wiley   +1 more source