Results 21 to 30 of about 21,763 (256)

Icariside Ⅱ Attenuates Palmitic Acid-Induced Endothelial Dysfunction Through SRPK1-Akt-eNOS Signaling Pathway

open access: yesFrontiers in Pharmacology, 2022
Background: Endothelial dysfunction is commonly accompanied by a reduced capacity for nitric oxide (NO) production and decreased NO sensitivity, playing a central role in numerous vascular diseases.
Yang-Yang Gu   +23 more
doaj   +1 more source

Community Knowledge, Perceptions, and Practices Associated with Urogenital Schistosomiasis among School-Aged Children in Zanzibar, United Republic of Tanzania [PDF]

open access: yes, 2016
Background: On the Zanzibar islands, United Republic of Tanzania, elimination of urogenital schistosomiasis is strived for in the coming years. This qualitative study aimed to better understand community knowledge, perceptions, and practices associated ...
A'Kadir, Faiza M   +20 more
core   +1 more source

Using Small Non-Coding RNAs in Extracellular Vesicles of Semen as Biomarkers of Male Reproductive System Health: Opportunities and Challenges [PDF]

open access: yes, 2023
Reproductive dysfunction and urogenital malignancies represent a serious health concern in men. This is in part as a result of the absence of reliable non-invasive tests of diagnosis/prognosis.
Sara Larriba   +5 more
core   +3 more sources

The Role of LIM Kinase in the Male Urogenital System

open access: yes, 2021
The LIM kinases (LIMK1 and LIMK2), known as downstream effectors, and the Rho-associated protein kinase (ROCK), a regulator of actin dynamics, have effects on a diverse set of cellular functions.
Soo Woong Kim, Min Chul Cho, Juhyun Park
core   +1 more source

Metabolism-Related Signature Analysis Uncovers the Prognostic and Immunotherapeutic Characteristics of Renal Cell Carcinoma

open access: yesFrontiers in Molecular Biosciences, 2022
Renal cell carcinoma (RCC) is one of the most common urological cancers. RCC has a poor prognosis and is considered a metabolic disease. It has been reported that many metabolic pathways are associated with the development of RCC. However, the prognostic
Jianye Zhang   +31 more
doaj   +1 more source

Copy Number Signatures and Clinical Outcomes in Upper Tract Urothelial Carcinoma

open access: yesFrontiers in Cell and Developmental Biology, 2021
Tumor staging of upper tract urothelial carcinomas (UTUCs) is relatively difficult to assert accurately before surgery. Here, we used copy number (CN) signatures as a tool to explore their clinical significance of molecular stratification in UTUC.
Bao Guan   +46 more
doaj   +1 more source

Simplified PI-RADS (S-PI-RADS) for biparametric MRI to detect and manage prostate cancer: What urologists need to know

open access: yesUrology Research and Practice, 2021
Biparametric magnetic resonance imaging (bpMRI) of the prostate has emerged as an alternative to multiparametric MRI (mpMRI) for the detection of clinically significant prostate cancer (csPCa).
Michele Scialpi   +7 more
doaj   +1 more source

Molecular genetics and pathophysiology of 17 beta-hydroxysteroid dehydrogenase 3 deficiency. [PDF]

open access: yes, 1996
Autosomal recessive mutations in the 17 beta-hydroxysteroid dehydrogenase 3 gene impair the formation of testosterone in the fetal testis and give rise to genetic males with female external genitalia.
Blethen, Sandra L.   +14 more
core   +1 more source

Steroid Hormones as Modulators of Emotional Regulation in Male Urogenital Cancers

open access: yes, 2023
Background Tumors develop within an organism operating in a specific social and physical environment. Cortisol and dehydroepiandrosterone (DHEA), two of the most abundant steroid hormones in humans, are involved in both emotional regulation and the tumor
Faviana, Pinuccia   +11 more
core   +1 more source

Thalidomide in plasma cell balanitis refractory to conventional topical treatment [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2018
: Zoon's plasma cell balanitis is a chronic genital inflammatory dermatosis that affects uncircumcised men, especially the elderly. It's characterized by painless erythematous plaques of orange hue, located on the glans penis and foreskin.
Lucas Mariano Serrão   +3 more
doaj   +1 more source

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